IL-24 Antikörper

Produktnummer ABIN1107832

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IL-24 in EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL-24 Antikörper (ABIN1107832)

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-24 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: B-C54

Produktdetails anti-IL-24 Antikörper

Spezifität: This Monoclonal antibody recognises both natural and recombinant Human IL-24 (Interleukin-24) also known as MDA-7 or TH2-specific cytokine FISP.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ion Exchange Chromatography

Immunogen: Recombinant Human IL-24. Myeloma X63/AG.8653 x Balb/c node cells.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS without carriers and preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu IL-24

Target: IL-24 (IL24) (Interleukin 24 (IL24))

Andere Bezeichnung: Interleukin-24 / IL24

Hintergrund: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein

Gen-ID: 11009

NCBI Accession: NP_001172085

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagie