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IL23A Antikörper

IL23A Reaktivität: Human IHC (p), Func Wirt: Maus Monoclonal B-Z23 unconjugated
Produktnummer ABIN1107827
  • Target Alle IL23A Antikörper anzeigen
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Reaktivität
    • 43
    • 19
    • 8
    • 1
    Human
    Wirt
    • 36
    • 7
    • 2
    • 1
    Maus
    Klonalität
    • 39
    • 7
    Monoklonal
    Konjugat
    • 32
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL23A Antikörper ist unkonjugiert
    Applikation
    • 32
    • 20
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
    Spezifität
    This antibody recognizes both recombinant and natural IL-23, p19 sub-unit.
    Aufreinigung
    Ion Exchange Chromatography
    Sterilität
    0.22 μm filtered
    Immunogen
    Recombinant Human IL-23 (sub-unit p19)
    Klon
    B-Z23
    Isotyp
    IgG1
    Top Product
    Discover our top product IL23A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Andere Bezeichnung
    Interleukin-23 alpha / IL23A (IL23A Produkte)
    Synonyme
    IL-23 antikoerper, IL-23A antikoerper, IL23P19 antikoerper, P19 antikoerper, SGRF antikoerper, FIL1 antikoerper, FIL1(ZETA) antikoerper, FIL1Z antikoerper, IL-1F7 antikoerper, IL-1H antikoerper, IL-1H4 antikoerper, IL-1RP1 antikoerper, IL-37 antikoerper, IL1F7 antikoerper, IL1H4 antikoerper, IL1RP1 antikoerper, p19 antikoerper, il23p19 antikoerper, IL23 antikoerper, interleukin 23 subunit alpha antikoerper, interleukin 37 antikoerper, interleukin 23, alpha subunit p19 antikoerper, IL23A antikoerper, IL37 antikoerper, Il23a antikoerper
    Hintergrund
    The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself, instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
    Gen-ID
    51561
    NCBI Accession
    NP_057668
    UniProt
    Q9NPF7
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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