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IL23A Antikörper
IL23A
Reaktivität: Human
IHC (p), Func
Wirt: Maus
Monoclonal
B-Z23
unconjugated
Produktnummer ABIN1107827
Produktdetails anti-IL23A Antikörper
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Target
Alle IL23A Antikörper anzeigen
IL23A
(Interleukin 23, alpha subunit p19 (IL23A))
Reaktivität
Alle Reaktivitäten für IL23A Antikörper
Human
Wirt
Alle Wirte für IL23A Antikörper
Maus
Klonalität
Alle Klonalitäten für IL23A Antikörper
Monoklonal
Konjugat
Alle Konjugate für IL23A Antikörper
Dieser IL23A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL23A Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func)
Spezifität
This antibody recognizes both recombinant and natural IL-23, p19 sub-unit.
Aufreinigung
Ion Exchange Chromatography
Sterilität
0.22 μm filtered
Immunogen
Recombinant Human IL-23 (sub-unit p19)
Klon
B-Z23
Isotyp
IgG1
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.
Konservierungsmittel
Without preservative
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Details zu IL23A
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Target
IL23A
(Interleukin 23, alpha subunit p19 (IL23A))
Andere Bezeichnung
Interleukin-23 alpha / IL23A (IL23A Produkte )
Synonyme
IL-23 antikoerper, IL-23A antikoerper, IL23P19 antikoerper, P19 antikoerper, SGRF antikoerper, FIL1 antikoerper, FIL1(ZETA) antikoerper, FIL1Z antikoerper, IL-1F7 antikoerper, IL-1H antikoerper, IL-1H4 antikoerper, IL-1RP1 antikoerper, IL-37 antikoerper, IL1F7 antikoerper, IL1H4 antikoerper, IL1RP1 antikoerper, p19 antikoerper, il23p19 antikoerper, IL23 antikoerper, interleukin 23 subunit alpha antikoerper, interleukin 37 antikoerper, interleukin 23, alpha subunit p19 antikoerper, IL23A antikoerper, IL37 antikoerper, Il23a antikoerper
Hintergrund
The p19 shares sequence similarity with IL-6 subfamily members and is distantly related to the p35 subunit of IL-12. It shows no biological activity by itself, instead, it combines with the p40 subunit of IL-12 to form a biologically active, composite cytokine, IL-23. IL-23 shares some in vivo functions with IL-12, including the activation of the transcription factor Stat4. Similar to IL-12, human IL-23 stimulates IFN-g production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells. Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gen-ID
51561
NCBI Accession
NP_057668
UniProt
Q9NPF7
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
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