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IL-2 Antikörper (PE)

IL2 Reaktivität: Human FACS Wirt: Maus Monoclonal B-G5 PE

Produktnummer ABIN1107825

Datenblatt (PDF)

Target Alle IL-2 (IL2) Antikörper anzeigen

IL-2 (IL2) (Interleukin 2 (IL2))
Reaktivität
155

96

42

13

9

7

6

6

4

4

4

4

3

2

1

1

1

1
Human
Wirt
117

82

79

11

4

2

1
Maus
Passende Sekundärantikörper
Klonalität
164

129

1
Monoklonal
Konjugat
156

37

24

20

17

9

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser IL-2 Antikörper ist konjugiert mit PE
Applikation
165

136

86

63

43

28

27

21

14

14

13

13

13

11

10

8

8

6

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Recognizes both natural and recombinant Human Interleukin-2 (IL-2).

Kreuzreaktivität (Details)

Species reactivity (tested):Human.

Aufreinigung

Ion Exchange Chromatography

Immunogen

Natural Human IL2

Klon

B-G5

Isotyp

IgG1

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Rekonstitution

Restore with 1 mL deionized water.

Buffer

PBS, 0.09 % Sodium Azide, 5 % BSA

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

DO NOT FREEZE!

Lagerung

4 °C

Informationen zur Lagerung

Store the antibody at 2-8 °C after reconstitution.
Target

IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung

Interleukin-2 / IL2 (IL2 Produkte)

Hintergrund

Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID

3558

NCBI Accession

NP_000577

UniProt

P60568

Pathways

JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation