IL-2 Antikörper (PE)

Produktnummer ABIN1107825

Dieses Anti-IL-2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL-2 in FACS. Geeignet für Human.

Kurzübersicht für IL-2 Antikörper (PE) (ABIN1107825)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: B-G5

Produktdetails anti-IL-2 Antikörper (PE)

Spezifität: Recognizes both natural and recombinant Human Interleukin-2 (IL-2).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ion Exchange Chromatography

Immunogen: Natural Human IL2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 1 mL deionized water.

Buffer: PBS, 0.09 % Sodium Azide, 5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2-8 °C after reconstitution.

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2 / IL2

Hintergrund: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID: 3558

NCBI Accession: NP_000577

UniProt: P60568

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation