IL-2 Antikörper

Produktnummer ABIN1107821

Der Maus Monoklonal Anti-IL-2-Antikörper wurde für WB, FACS und Func validiert. Er ist geeignet, IL-2 in Proben von Human zu detektieren.

Kurzübersicht für IL-2 Antikörper (ABIN1107821)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Functional Studies (Func)

Klon: B-G5

Produktdetails anti-IL-2 Antikörper

Spezifität: Recognizes both natural and recombinant Human Interleukin-2 (IL-2).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ion Exchange Chromatography

Sterilität: 0.22 μm filtered

Immunogen: Natural Human IL-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS without Carrier and preservatives. This product is Sterile-filtered through 0.22 μm and treated to remove endotoxins.

Konservierungsmittel: Without preservative

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: Interleukin-2 / IL2

Hintergrund: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

Gen-ID: 3558

NCBI Accession: NP_000577

UniProt: P60568

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation