Deoxyuridine Triphosphatase (DUT) (Middle Region) Antikörper
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- Target Alle Deoxyuridine Triphosphatase (DUT) Antikörper anzeigen
- Deoxyuridine Triphosphatase (DUT)
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Spezifität
- This antibody detects DUT in the middle. No cross reactivity with other roteins.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
- Aufreinigung
- Immunogen affinity purified
- Immunogen
- Synthetic peptide corresponding to a sequence mapping at the middle region of human dUTPase .Remarks: Sequence is identical to the related rat and ouse sequence.
- Isotyp
- IgG
- Top Product
- Discover our top product DUT Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg himerosal, 0.05 mg NaN3
- Konservierungsmittel
- Sodium azide, Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- Deoxyuridine Triphosphatase (DUT)
- Andere Bezeichnung
- DUT (DUT Produkte)
- Synonyme
- BcDNA:LD08534 antikoerper, CG4584 antikoerper, Dmel\\CG4584 antikoerper, LD08534 antikoerper, UTPase antikoerper, anon-SAGE:Wang-077 antikoerper, dUTPase antikoerper, Tb07.27E10.390 antikoerper, dutpase antikoerper, 5031412I06Rik antikoerper, 5133400F09Rik antikoerper, D2Bwg0749e antikoerper, Dutp antikoerper, PIP4 antikoerper, deoxyuridine triphosphatase antikoerper, Deoxyuridine triphosphatase antikoerper, dUTPase; ORF54; similar to EBV BLLF3, CMV UL72, HSV UL50 antikoerper, involved in nucleotide metabolism antikoerper, tegument protein antikoerper, dUTPase antikoerper, deoxyuridine triphosphatase L homeolog antikoerper, DUT antikoerper, dUTPase antikoerper, P18 antikoerper, AlHV1gp51 antikoerper, UL50 antikoerper, HVT058 antikoerper, ORF9 antikoerper, ORF8 antikoerper, U45 antikoerper, GAMMAHV.ORF54 antikoerper, Tc00.1047053509151.130 antikoerper, Tc00.1047053508175.160 antikoerper, Tb927.7.5160 antikoerper, dut.L antikoerper, Dut antikoerper
- Substanzklasse
- Viral Protein
- Hintergrund
- Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is responsible for maintaining low ntracellular levels of dUTP, thus preventing the incorporation of dUTP into DNA. DUTPase ctivity/expression can be down-regulated using siRNA specifically targeted to dUTPase mRNA and UTPase plays a role in DNA nucleotide metabolism. This protein, present predominantly in the ytoplasm, contains 252 amino acids with a Mr of 26,704. It exhibits 35 % identity with the E. coli UTPase and 53 % identity with the Saccharomyces cerevisiae enzyme. The nuclear and mitochondrial orms of dUTPase are encoded by the same gene with isoform-specific transcripts arising through the se of alternative 5-prime exons. Human dUTPase exhibits 92 % identity with rat. Moreover, this nzyme has profound effects on the efficacy of agents that target thymidylate biosynthesis.Synonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase mitochondrial, dUTP pyrophosphatase, dUTPase
- Gen-ID
- 1854
- NCBI Accession
- NP_001020419
- UniProt
- P33316
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