Desmoglein 2 Antikörper (Extracellular Domain)
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- Target Alle Desmoglein 2 (DSG2) Antikörper anzeigen
- Desmoglein 2 (DSG2)
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Bindungsspezifität
- Extracellular Domain
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Desmoglein 2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- The monoclonal antibody 6D8 recognizes the extracellular domain of human desmoglein-2. Does not cross react with desmoglein-1 and desmoglein-3.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human
- Aufreinigung
- Protein G
- Immunogen
- Extracellular EC4 domain
- Klon
- 6D8
- Isotyp
- IgG1
- Top Product
- Discover our top product DSG2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.1 mg/mL
- Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Desmoglein 2 (DSG2)
- Andere Bezeichnung
- Desmoglein-2 (DSG2 Produkte)
- Synonyme
- DSG2 antikoerper, dsc antikoerper, dsga antikoerper, si:dkeyp-51f12.6 antikoerper, wu:fj23f02 antikoerper, ARVC10 antikoerper, ARVD10 antikoerper, CDHF5 antikoerper, CMD1BB antikoerper, HDGC antikoerper, AA408168 antikoerper, D18Ertd293e antikoerper, desmoglein 2 antikoerper, desmoglein 2, tandem duplicate 1 antikoerper, DSG2 antikoerper, dsg2.1 antikoerper, dsg2 antikoerper, Dsg2 antikoerper
- Hintergrund
- Desmogleins and desmocollins are members of the cadherin family of transmembrane proteins that together make up the core of the desmosome, a structure that provides transmembrane strength to tissues undergoing mechanical stress. The desmosomal cadherins, desmogleins and desmocollins, mediate calcium-dependent cell-cell adhesion by forming homotypic and heterotypic interactions with one another. The multiprotein desmosomal complex also includes the cytoplasmic desmosomal plaque proteins plakoglobin, phakophilins, and desmoplakin, which bind to the intracellular domain of the desmogleins and function to anchor the keratin intermediate filament network to site of cell-cell contacts.Synonyms: CDHF5, Cadherin family member 5, DSG2, HDGC
- Gen-ID
- 1829
- NCBI Accession
- NP_001934
- UniProt
- Q14126
- Pathways
- Cell-Cell Junction Organization
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