Dieses Anti-Collagen Type V-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Collagen Type V in WB, IHC (fro), IP und EIA. Geeignet für Human.
Produktnummer ABIN1106760
Kurzübersicht für Collagen Type V Antikörper (ABIN1106760)
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore in distilled water
Konzentration
1 mg/mL
Buffer
0.1 M Tris, 0.1 M Glycine, 2 % Sucrose, None
Target
Collagen Type V (COL5)
(Collagen, Type V (COL5))
Andere Bezeichnung
Collagen Type V
Hintergrund
Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure.Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1