Collagen Type V Antikörper

Produktnummer ABIN135054

Zitiert in 3+ Publikationen. Der Ziege Polyklonal anti-Collagen Type V Antikörper (ABIN135054) detektiert spezifisch Collagen Type V in WB, ELISA, IHC (fro), IHC (p), ICC und IEM. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Huhn, Meerschweinchen, Pferd, Schwein, Kaninchen, Sepiidae und Tree shrew.

Kurzübersicht für Collagen Type V Antikörper (ABIN135054)

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Reaktivität: Human, Ratte, Maus, Hund, Huhn, Meerschweinchen, Pferd, Schwein, Kaninchen, Sepiidae, Tree shrew

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Collagen Type V Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Produktdetails anti-Collagen Type V Antikörper

Verwendungszweck: Goat Anti-Type V Collagen-UNLB

Spezifität: Reacts with conformational determinants on type V collagen Referenced species reactivities include - Human 2,5,6,11,13,14,17,23-26 Chicken 4 Porcine 1,5,8 Mouse 3,12,20 Cuttlefish 27 Rabbit 9,15 Rat 5,7,10,16 Equine 19,21,22 Tree Shrew 18 Canine 5 Guinea Pig 15

Kreuzreaktivität (Details): Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

Produktmerkmale: Purified Anti-Type V Collagen antibody for use in ELISA, immunohistochemistry / immunocytochemistry, electron microscopy, and western blotting assays.

Aufreinigung: Purified by affinity chromatography on type V collagen covalently linked to agarose, cross-adsorbed against Collagen types I, II, III, IV, and VI for minimal reactivity

Immunogen: Type V collagen

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Pooled antisera from goats hyperimmunized with type V collagen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: Borate buffered saline, pH 8.2

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Referenzen für anti-Collagen Type V Antikörper (ABIN135054)

Welc, Flores, Wehling-Henricks, Ramos, Wang, Bertoni, Tidball: "Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy." in: Nature communications, Vol. 10, Issue 1, pp. 2788, (2019) (PubMed).

Finno, Gianino, Perumbakkam, Williams, Bordbari, Gardner, Burns, Peng, Durward-Akhurst, Valberg: "A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses." in: Skeletal muscle, Vol. 8, Issue 1, pp. 7, (2018) (PubMed).

Huang, Ge, Izzi, Greenspan: "α3 Chains of type V collagen regulate breast tumour growth via glypican-1." in: Nature communications, Vol. 8, pp. 14351, (2018) (PubMed).

Details zu Collagen Type V

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Andere Bezeichnung: TypeV Collagen

Hintergrund:

Description: Goat Anti-Type V Collagen-UNLB

NCBI_Official_Symbol: COL5A1, COL5A2, COL5A3

Synoynms: COL5

Gen-ID: 1289, 1290

UniProt: P20908