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FAS Antikörper

FAS Reaktivität: Human WB, FACS, Neut Wirt: Maus Monoclonal ZB4 unconjugated
Produktnummer ABIN1106613
  • Target Alle FAS Antikörper anzeigen
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Reaktivität
    • 227
    • 63
    • 62
    • 19
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 156
    • 107
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 154
    • 116
    • 1
    Monoklonal
    Konjugat
    • 122
    • 27
    • 25
    • 13
    • 12
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAS Antikörper ist unkonjugiert
    Applikation
    • 159
    • 131
    • 71
    • 60
    • 41
    • 34
    • 29
    • 26
    • 26
    • 19
    • 16
    • 15
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Neutralization (Neut)
    Spezifität
    This antibody reacts with Fas.
    Keine Kreuzreaktivität
    Maus
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein A agarose
    Immunogen
    Recombinant human Fas
    Klon
    ZB4
    Isotyp
    IgG1
    Top Product
    Discover our top product FAS Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2
    Konservierungsmittel
    Azide free
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store (in aliquots) at -20 °C.
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Andere Bezeichnung
    CD95 / FAS (FAS Produkte)
    Hintergrund
    It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas (also known as CD95/APO-1) is a cell surface protein belonging to the tumor necrosis factor receptor superfamily, which is expressed in a variety of normal and neoplastic cells. Binding of FasL to Fas or crosslinking of Fas by anti-Fas monoclonal antibodies results in rapid induction of apoptosis in Fas expressing cells. Clone ZB4 is known as Fas blocking, Fas neutralizing or Fas antagonistic antibody, whereas anti-human Fas antibody (clone CH-11) is known as the agonistic antibody.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6
    Gen-ID
    355
    NCBI Accession
    NP_000034
    UniProt
    P25445
    Pathways
    p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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