FAS Antikörper

Produktnummer ABIN1106612

Der Ratte Monoklonal Anti-FAS-Antikörper wurde für FACS validiert. Er ist geeignet, FAS in Proben von Maus zu detektieren.

Kurzübersicht für FAS Antikörper (ABIN1106612)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser FAS Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: RMF6

Produktdetails anti-FAS Antikörper

Spezifität: This antibody reacts with Fas (CD95 antigen).

Kreuzreaktivität (Details): Species reactivity (tested):Mouse

Aufreinigung: Ammonium sulfate precipitation and affinity chromatography on protein G agaroseProtein G agarose

Immunogen: Recombinant chimera protein of mouse soluble Fas and AIC2A

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store (in aliquots) at -20 °C.

Details zu FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Andere Bezeichnung: CD95 / FAS

Hintergrund: It is now widely accepted that apoptosis plays an important role in the selection of immature thymocytes and Ag-primed peripheral T cells. Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has structural homology with a number of cell-surface receptors, including tumor necrosis factor receptor and nerve growth factor receptor.Synonyms: APT1, Apo-1 antigen, FAS1, FASLG receptor, TNFRSF6, Tumor necrosis factor receptor superfamily member 6

Gen-ID: 14102

NCBI Accession: NP_032013

UniProt: P25446

Pathways: p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity