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F11R Antikörper

F11R Reaktivität: Maus IHC (fro) Wirt: Ratte Monoclonal 27-09-14 unconjugated
Produktnummer ABIN1106263
$629.20
Zzgl. Versandkosten $45.00
0.1 mg
Available
  • Target Alle F11R Antikörper anzeigen
    F11R (F11 Receptor (F11R))
    Reaktivität
    • 71
    • 38
    • 29
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 53
    • 15
    • 14
    • 7
    • 2
    Ratte
    Klonalität
    • 54
    • 34
    Monoklonal
    Konjugat
    • 46
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser F11R Antikörper ist unkonjugiert
    Applikation
    • 52
    • 25
    • 19
    • 16
    • 15
    • 14
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro))
    Aufreinigung
    This antibody was purified from hybridoma (clone 27-9) supernatant using protein G agarose. This hybridoma was established by fusion of mouse myeloma cell P3X with Wister rat lymphocyte immunized with E14.5 mouse fetal liver cells.
    Klon
    27-09-14
    Isotyp
    IgG2a
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2 containing no preservative
  • Target
    F11R (F11 Receptor (F11R))
    Andere Bezeichnung
    CD321 / JAM1 (F11R Produkte)
    Synonyme
    CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1, 9130004G24, AA638916, ESTM33, JAM-1, JAM-A, Jcam, Jcam1, Ly106, Jam1, F11 receptor, F11R, F11r
    Hintergrund
    Junctional adhesion molecules (JAMs) are member of the immunoglobulin superfamily. JAMs play an important role in many cellular processes such as tight junction assembly, leukocyte transmigration, platelet activation, angiogenesis and virus binding. JAM-A is a 37 kDa protein also called JAM-1 or F11R. JAM-A is expressed on endothelial cells, epithelial cells, and also hematopoietic cells such as neutrophils, platelets, monocytes, lymphocyte and erythrocyte. Extracellular domain of JAM-A participates in homophilic interaction stabilizing endothelial or epithelial cell-cell junctions particularly around tight junctions. In addition, JAM-A is important in leukocyte transmigration. Not only homophilic JAM-A interactions between leukocytes and the endothelium but also heterophilic interactions of JAM-A with the β2-integrin leukocyte function-associated antigen-1 (LFA-1) are considered to mediate leukocyte transmigration.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1
    Pathways
    Cell-Cell Junction Organization
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