Syndecan 1 Antikörper

Produktnummer ABIN1105859

Produktdetails anti-Syndecan 1 Antikörper

Target: Syndecan 1 (SDC1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Syndecan 1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: The antibody B-A38 recognizes CD138 (Syndecan-1), a 65-70 kDa heparan sulfate proteoglycan expressed mainly in the epidermis and plasma cells, but also in growth factor-stimulated lymphocytes.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ion Exchange Chromatography

Klon: B-A38

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Azide Free PBS, pH 7.4, 0.2 μm filter sterilized, None

Konservierungsmittel: Azide free

Details zu Syndecan 1

Target: Syndecan 1 (SDC1)

Andere Bezeichnung: CD138 / Syndecan-1 (SDC1 Produkte)

Hintergrund: CD138 (syndecan-1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.Synonyms: SDC, SDC1, SYND1

Gen-ID: 6382

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism