MAP3K14 Antikörper
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- Target Alle MAP3K14 Antikörper anzeigen
- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAP3K14 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Top Product
- Discover our top product MAP3K14 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Lagerung
- 4 °C
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- Target
- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
- Andere Bezeichnung
- NIK (NF-kB-Inducing Kinase) (MAP3K14 Produkte)
- Synonyme
- FTDCR1B antikoerper, HS antikoerper, HSNIK antikoerper, NIK antikoerper, F23F1.4 antikoerper, F23F1_4 antikoerper, mitogen-activated protein kinase kinase kinase 14 antikoerper, Nik antikoerper, aly antikoerper, mitogen-activated protein kinase kinase kinase 14 antikoerper, MAP3K14 antikoerper, Map3k14 antikoerper, MAPKKK14 antikoerper
- Hintergrund
- NIK (NF-. B-inducing kinase) is a member of the MAP kinase kinase kinase family that binds TRAF2 and stimulates NF-. B activity. NIK, initially isolated from a human B cell cDNA library, contains 795 amino acids with an apparent molecular weight of slightly more than 97 kDa on SDS gel. NIK is a serine/threonine kinase and its kinase activity contributes to I. B phosphorylation. The carboxyl terminal segment of NIK binds TRAF2. A mutant NIK with intact carboxyl terminus but without the two lysine residues at its catalytic domain serves as a dominant-negative inhibitor for NF-. B activation. NIK also interacts with TRAF6 and mediates IL-1-induced NF-. B activation.
- Pathways
- NF-kappaB Signalweg, T-Zell Rezeptor Signalweg
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