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VCAM1 Antikörper
VCAM1
Reaktivität: Human
FACS, Func, EIA
Wirt: Maus
Monoclonal
B-K9
unconjugated
Produktnummer ABIN1105738
Produktdetails anti-VCAM1 Antikörper
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Target
Alle VCAM1 Antikörper anzeigen
VCAM1
(Vascular Cell Adhesion Molecule 1 (VCAM1))
Reaktivität
Alle Reaktivitäten für VCAM1 Antikörper
Human
Wirt
Alle Wirte für VCAM1 Antikörper
Maus
Klonalität
Alle Klonalitäten für VCAM1 Antikörper
Monoklonal
Konjugat
Alle Konjugate für VCAM1 Antikörper
Dieser VCAM1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für VCAM1 Antikörper
Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)
Spezifität
Recognizes the Vascular Cellular Adhesion Molecule-1 (VCAM-1), a 110 kDa protein. Recognizes the soluble antigen.
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Ion Exchange Chromatography.
Sterilität
0.22 μm filtered
Immunogen
Activated Human umbilical vein endothelial. cells. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.
Klon
B-K9
Isotyp
IgG1
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Discover our top product VCAM1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1.0 mg/mL
Buffer
Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.
Konservierungsmittel
Without preservative
Lagerung
4 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C.
Details zu VCAM1
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Target
VCAM1
(Vascular Cell Adhesion Molecule 1 (VCAM1))
Andere Bezeichnung
CD106 / VCAM1 (VCAM1 Produkte )
Synonyme
CD106 antikoerper, INCAM-100 antikoerper, Vcam-1 antikoerper, VCAM1B antikoerper, fi76d06 antikoerper, wu:fi76d06 antikoerper, zgc:158875 antikoerper, VCAM1 antikoerper, vascular cell adhesion molecule 1 antikoerper, vascular cell adhesion molecule 1b antikoerper, VCAM1 antikoerper, Vcam1 antikoerper, vcam1b antikoerper, VCAM-1 antikoerper
Hintergrund
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.Synonyms: INCAM-100, L1CAM, V-CAM 1, VCAM-1, Vascular cell adhesion protein 1
Gen-ID
7412
NCBI Accession
NP_001069
UniProt
P19320
Pathways
Carbohydrate Homeostasis
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