VCAM1 Antikörper

Produktnummer ABIN1105738

Dieses Maus Monoklonal-Antikörper erkennt spezifisch VCAM1 in FACS, Func und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für VCAM1 Antikörper (ABIN1105738)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VCAM1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func), Enzyme Immunoassay (EIA)

Klon: B-K9

Produktdetails anti-VCAM1 Antikörper

Spezifität: Recognizes the Vascular Cellular Adhesion Molecule-1 (VCAM-1), a 110 kDa protein. Recognizes the soluble antigen.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Ion Exchange Chromatography.

Sterilität: 0.22 μm filtered

Immunogen: Activated Human umbilical vein endothelial. cells. Hybridoma: Myeloma X63/AG.8653 x Balb/c spleen cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate-buffered saline without Carrier and preservatives. This prodcut is sterile-filtered through 0.22 μm and treated to remove Endotoxins.

Konservierungsmittel: Without preservative

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: CD106 / VCAM1

Hintergrund: CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity. Soluble form of VCAM-1 (sVCAM-1) is an inflammatory marker and can be used also in prognosis of subsequent cariovascular events following acute coronary syndromes.Synonyms: INCAM-100, L1CAM, V-CAM 1, VCAM-1, Vascular cell adhesion protein 1

Gen-ID: 7412

NCBI Accession: NP_001069

UniProt: P19320

Pathways: Carbohydrate Homeostasis