CX3CL1 Antikörper (Intracellular)
Kurzübersicht für CX3CL1 Antikörper (Intracellular) (ABIN110564)
Target
Alle CX3CL1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Intracellular
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Lagerung
- 4 °C
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- CX3CL1 (Chemokine (C-X3-C Motif) Ligand 1 (CX3CL1))
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Andere Bezeichnung
- Fractalkine
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Hintergrund
- Fractalkine, also known as neurotactin, is a membrane-bound CX3C chemokine. The mature protein is part of a 397-amino acid precursor and consists of a chemokine domain of 76 amino acids, a mucin stalk of 241 amino acids, a putative transmembrane domain of 18 amino acids, and an intracellular tail of 37 amino acids. Within the chemokine domain the first two cysteine residues are separated by 3 amino acids (CX3C). Fractalkine message is found in high abundance in the brain, kidney, lung and heart tissues. Fractalkine is chemotactic for monocytes and other leukocytes including NK cells, lymphocytes, and may play a role in brain inflammation.
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Pathways
- Synaptic Membrane
Target
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