AMD1 Antikörper (C-Term)

Produktnummer ABIN1105345

Produktdetails anti-AMD1 Antikörper

Target: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody detects AMD1 (C-term). No cross reactivity with other proteins.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Immunogen affinity purified

Immunogen: Synthetic peptide corresponding to a sequence at the C-terminal of human SAMDC .Remarks: Sequence is identical to the related mouse and rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu AMD1

Target: AMD1 (Adenosylmethionine Decarboxylase 1 (AMD1))

Andere Bezeichnung: AMD1 (AMD1 Produkte)

Synonyme: ADOMETDC antikoerper, AMD antikoerper, SAMDC antikoerper, Amd1a antikoerper, Amd1b antikoerper, AMD1 antikoerper, AdoMetDC antikoerper, amd antikoerper, samdc antikoerper, fb26e03 antikoerper, si:ch211-257g8.2 antikoerper, wu:fb26e03 antikoerper, zgc:55614 antikoerper, 1 antikoerper, Amd-1 antikoerper, SAMDC 1 antikoerper, adoMetDC1 antikoerper, CG5029 antikoerper, Dmel\\CG5029 antikoerper, l(2)31Dc antikoerper, l(2)31Dd antikoerper, l(2)31De antikoerper, F16B3.10 antikoerper, F16B3_10 antikoerper, S-ADENOSYLMETHIONINE DECARBOXYLASE antikoerper, S-adenosylmethionine decarboxylase antikoerper, adenosylmethionine decarboxylase 1 antikoerper, S-adenosylmethionine decarboxylase 1 antikoerper, S-adenosyl methionine decarboxylase 2 antikoerper, adenosylmethionine decarboxylase 1 L homeolog antikoerper, S-adenosylmethionine decarboxylase antikoerper, AMD1 antikoerper, Amd1 antikoerper, amd1 antikoerper, sam2 antikoerper, amd1.L antikoerper, SamDC antikoerper, SAMDC antikoerper

Hintergrund: S-adenosylmethionine decarboxylase (AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme (SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.Synonyms: AdoMetDC, S-adenosylmethionine decarboxylase proenzyme, SAMDC

Gen-ID: 262

NCBI Accession: NP_001625

UniProt: P17707

Pathways: Ribonucleoside Biosynthetic Process