Der Maus Monoklonal anti-ACTN1 Antikörper wird verwendet zum Nachweis von ACTN1 in Proben von Human, Maus, Ratte und Kaninchen. Er wurde validiert für WB, IF, IHC (p) und IP.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore with 1.2 % sodium acetate or neutral PBS
Konzentration
0,1 mg/mL
Buffer
1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
ACTN1
(Actinin, alpha 1 (ACTN1))
Andere Bezeichnung
alpha-Actinin-1 / ACTN1
Hintergrund
Alpha-actinin was initially isolated from rabbit skeletal muscle as a factor that induces the gelation of F-actin and promotes the superprecipitation of actomyosin. Alpha actinins are actin-binding proteins that carry out different purposes in different different cell types. In myofibrillar cells, alpha-actinin constitutes a major component of Z-discs in striated muscle and of the functionally analogous dense bodies and dense plaques in smooth muscle. alpha-actinin (alpha A) shares structural homology with spectrin and dystrophin.Synonyms: Alpha actinin cytoskeletal isoform, F-actin cross-linking protein, Non-muscle alpha-actinin 1