Neuregulin 1 Antikörper

Produktnummer ABIN1103330

Produktdetails anti-Neuregulin 1 Antikörper

Target: Neuregulin 1 (NRG1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuregulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Neutralization (Neut)

Marke: IHC-plus™

Spezifität: Human Heregulin-beta1

Aufreinigung: Immunoaffinity purified

Immunogen: E.coli derived recombinant Human Heregulin-beta1.

Type of Immunogen: Cell extract

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, IHC, IHC-P (5 μg/mL), Neut, WB

Usage: Immunohistochemistry: LS-B7486 in an IHC-plus antibody, validated by our pathologists for use in IHC against formalin-fixed, paraffin-embedded human tissues (IHC validation procedure). A concentration of 5 μg/mL is recommended. Neutralization: To yield one-half maximal inhibition [ND] of the biological activity of Human Heregulin-beta1 (1 ng/mL), a concentration of 0.7-1.1 μg/mL of this antibody is required. ELISA: To detect Human Heregulin-beta1 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Human Heregulin-beta1(LS-C104552) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant Human Heregulin-beta1. Western Blot: To detect Human Heregulin-beta1 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. When used in conjunction with compatible secondary reagents, the detection limit for recombinant Human Heregulin-beta1 is 1.5-3 ng/lane, under either reducing or non-reducing conditions.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Sterile water

Konzentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.2

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store Lyophilized at room temperature up to 1 month
Reconstituted for up to 2 weeks at 2-8°C. Aliquot and freeze at -20°C for long term storage. Avoid freeze/thaw cycles.

Details zu Neuregulin 1

Target: Neuregulin 1 (NRG1)

Andere Bezeichnung: NRG1 / Heregulin / Neuregulin (NRG1 Produkte)

Synonyme: 6030402G23Rik antikoerper, ARIA antikoerper, D230005F13Rik antikoerper, GGF antikoerper, GGFII antikoerper, HRG antikoerper, HRGalpha antikoerper, Hgl antikoerper, NDF antikoerper, SMDF antikoerper, GGF2 antikoerper, HGL antikoerper, HRG1 antikoerper, HRGA antikoerper, MST131 antikoerper, NRG-1 antikoerper, heregulin antikoerper, nrg1-A antikoerper, pro-neuregulin-1 antikoerper, NRG1 antikoerper, wu:fm70e01 antikoerper, DKFZp459A1838 antikoerper, neuregulin 1 antikoerper, histidine rich glycoprotein antikoerper, neuregulin 1 L homeolog antikoerper, Nrg1 antikoerper, NRG1 antikoerper, HRG antikoerper, nrg1.L antikoerper, nrg1 antikoerper

Hintergrund: Name/Gene ID: NRG1

Synonyms: NRG1, ARIA, GGF, GGF2, Glial growth factor, Heregulin, HRGA, MSTP131, NDF, Neu differentiation factor, Neuregulin 1 type IV beta 3, Neuregulin 1 type IV beta 1a, HRG1, NRG-1, SMDF, Neuregulin 1, Pro-NRG1, HGL, MST131

Gen-ID: 3084

UniProt: Q02297

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation