Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper

Produktnummer ABIN1098196

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in IHC, WB und IF/ICC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) Antikörper (ABIN1098196)

Target: Cav3.1 Ca2+ Channel

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Klon: S178A-9

Produktdetails

Bindungsspezifität: AA 2052-2172, C-Term

Verwendungszweck: Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody

Spezifität: This antibody recognizes human, mouse, and rat Cav3.1. It does not cross-react with Cav3.2.

Kreuzreaktivität: Human, Maus, Ratte

Kreuzreaktivität (Details): No cross Reactivity with Cav3.2

Aufreinigung: Purified by Protein G affinity chromatography.

Immunogen: Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain membranes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C.

Antigendetails

Target: Cav3.1 Ca2+ Channel

Andere Bezeichnung: Cav3.1 Ca+2 Channel

Hintergrund: Voltage-dependent T-type calcium channel subunit α,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage- activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and antiepileptics and possibly in some anesthetics and antipsychotics.

NCBI Accession: NP_001106284

UniProt: Q9WUT2