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FOXP1 Antikörper (AA 481-677)

FOXP1 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 6E4 unconjugated
Produktnummer ABIN1098120
  • Target Alle FOXP1 Antikörper anzeigen
    FOXP1 (Forkhead Box P1 (FOXP1))
    Bindungsspezifität
    • 16
    • 10
    • 10
    • 9
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 481-677
    Reaktivität
    • 87
    • 56
    • 30
    • 19
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Wirt
    • 88
    • 18
    • 2
    Maus
    Klonalität
    • 75
    • 32
    • 1
    Monoklonal
    Konjugat
    • 61
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FOXP1 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 38
    • 38
    • 32
    • 14
    • 12
    • 11
    • 10
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    FOXP1 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human FOXP1 (AA: 481-677) expressed in E. Coli.
    Klon
    6E4
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

    Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

  • Target
    FOXP1 (Forkhead Box P1 (FOXP1))
    Andere Bezeichnung
    FOXP1 (FOXP1 Produkte)
    Hintergrund
    This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
    Molekulargewicht
    75.3 kDa
    UniProt
    Q9H334
    Pathways
    Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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