FOXP1 Antikörper (AA 481-677)

Produktnummer ABIN1098120

Dieses Anti-FOXP1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von FOXP1 in WB, ELISA, IHC und FACS. Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für FOXP1 Antikörper (AA 481-677) (ABIN1098120)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 6E4

Produktdetails anti-FOXP1 Antikörper

Bindungsspezifität: AA 481-677

Verwendungszweck: FOXP1 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human FOXP1 (AA: 481-677) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FOXP1 Antikörper (ABIN1098120)

Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

Details zu FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Andere Bezeichnung: FOXP1

Hintergrund: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 75.3 kDa

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response