FOXP1 Antikörper (N-Term)

Produktnummer ABIN2779725

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FOXP1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für FOXP1 Antikörper (N-Term) (ABIN2779725)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FOXP1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FOXP1 Antibody - N-terminal region

Sequenz: MIPTELQQLW KEVTSAHTAE ETTGNNHSSL DLTTTCVSSS APSKTSLI

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FOXP1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32564-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FOXP1 Antikörper (ABIN2779725)

Tang, Becanovic, Desplats, Spencer, Hill, Connolly, Masliah, Leavitt, Thomas: "Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease." in: Human molecular genetics, Vol. 21, Issue 14, pp. 3097-111, (2012) (PubMed).

Konstantoulas, Parmar, Li: "FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3." in: Journal of neurochemistry, Vol. 113, Issue 4, pp. 836-47, (2010) (PubMed).

Jepsen, Gleiberman, Shi, Simon, Rosenfeld: "Cooperative regulation in development by SMRT and FOXP1." in: Genes & development, Vol. 22, Issue 6, pp. 740-5, (2008) (PubMed).

Details zu FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Andere Bezeichnung: FOXP1

Hintergrund:

Background Information: FOXP1 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s).

Gene Name: Forkhead box P1

Alternative Symbols: MFH, QRF1, 12CC4, hFKH1B, HSPC215

Protein Name: Forkhead box protein P1

Molekulargewicht: 75kDa

Gen-ID: 27086

NCBI Accession: NP_116071

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response