CEACAM1/5 Antikörper

Produktnummer ABIN108735

Dieses Anti-CEACAM1/5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CEACAM1/5 in FACS, WB, ELISA, cELISA und IHC (fro). Geeignet für Human.

Kurzübersicht für CEACAM1/5 Antikörper (ABIN108735)

Target: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1/5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Cell-ELISA (cELISA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 4-3-17

Produktdetails anti-CEACAM1/5 Antikörper

Spezifität: Anti-human CEACAM1, 5 (BGP, CEA, CD66a,e)

Aufreinigung: Protein G

Immunogen: immunisation with extracted protein of CEACAM5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 Western blot: 4 µg/mL
Immunohistology: 1-2 µg/10^6 cells (on cryosections)
For each application a titration should be performed to determine the optimal concentration.

Kommentare:

Synonyms: CD66ae, BGP, CEA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu CEACAM1/5

Target: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Andere Bezeichnung: CEACAM1,5

Hintergrund: Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker CEACAM1 expression is down-regulated in many tumors indicating a tumor-suppressive function. The anti-tumor effect may be due to inhibition of tumor angiogenesis, possibly by increased secretion of anti-angiogenic molecules from the cells. The function of CEA family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.

UniProt: P06731, P13688