CEACAM1/5 Antikörper (CF®488A)

Produktnummer ABIN6933700

Produktdetails anti-CEACAM1/5 Antikörper (CF®488A)

Target: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM1/5 Antikörper ist konjugiert mit CF®488A

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Spezifität: This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

Kreuzreaktivität (Details): Human,

Aufreinigung: Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules.

Immunogen: Recombinant full-length human CEA protein

Klon: C66-1009

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Positive Control: MCF7 or 293T cells. Colon carcinoma.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Haltbarkeit: 24 months

Details zu CEACAM1/5

Target: CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Andere Bezeichnung: CEACAM1 & CEACAM5 (CEACAM1/5 Produkte)

Synonyme: CD66e antikoerper, CEA antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, CEACAM5 antikoerper

Hintergrund: Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1),Carcinoembryonic Antigen (CEA) / CD66
Cellular localisation: Cytoplasmic and luminal surface

Molekulargewicht: 80-200kDa

Gen-ID: 1048, 634, 709196

UniProt: P06731