ICOSLG Antikörper (Extracellular Domain)

Produktnummer ABIN108723

Produktdetails anti-ICOSLG Antikörper

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Bindungsspezifität: Extracellular Domain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICOSLG Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Spezifität: GM13C1 recognises the extracellular domain of ICOSL transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on antigen presenting cells (see reference).

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding human ICOSL (extracellular domain)

Klon: GM-13C1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Kommentare:

Synonyms: ICOS ligand

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Andere Bezeichnung: ICOSL (ICOSLG Produkte)

Hintergrund: The inducible co-stimulator receptor (ICOS) is a member of the CD28 receptor family that is expressed on T cells. ICOS ligand (ICOSL) has been identified as a ligand that binds to ICOS, but not to CD28 or CTLA4. GM13C1 was generated by genetic immunisation and recognises the extracellular domain of ICOSL.

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation