IL13RA2 Antikörper (Extracellular Domain)

Produktnummer ABIN108717

Dieses Anti-IL13RA2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL13RA2 in ELISA, FACS und cELISA. Geeignet für Human.

Kurzübersicht für IL13RA2 Antikörper (Extracellular Domain) (ABIN108717)

Target: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL13RA2 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Cell-ELISA (cELISA)

Klon: GM-1C8

Produktdetails anti-IL13RA2 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: GM1C8 recognises IL-13Ralpha1 transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes (Myrtek et al., 2004).

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding human IL13-Ralpha1 (extracellular domain)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu IL13RA2

Target: IL13RA2 (Interleukin 13 Receptor, alpha 2 (IL13RA2))

Andere Bezeichnung: IL13R

Hintergrund: Interleukin 13 (IL-13) is a T cell derived cytokine involved in the regulation of inflammatory and im-mune responses. IL-13Rα1 together with IL-4Rα forms a functional receptor for both IL-4 and IL-13, which is why these two cytokines share many of their biological activities. The receptor is found on human B cells, monocytes and endothelial cells. However, no functional receptor is expressed on T cells, which explains why IL-13, in contrast to IL-4, fails to induce TH2-cell differentiation.

UniProt: P78552