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CD31 Antikörper

PECAM1 Reaktivität: Human WB, IHC Wirt: Maus Monoclonal CE6 unconjugated
Produktnummer ABIN108424
  • Target Alle CD31 (PECAM1) Antikörper anzeigen
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Reaktivität
    • 270
    • 149
    • 75
    • 59
    • 44
    • 31
    • 21
    • 20
    • 11
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 164
    • 140
    • 54
    • 8
    • 6
    • 3
    • 2
    Maus
    Klonalität
    • 241
    • 127
    • 8
    • 1
    Monoklonal
    Konjugat
    • 163
    • 33
    • 31
    • 25
    • 13
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser CD31 Antikörper ist unkonjugiert
    Applikation
    • 240
    • 180
    • 106
    • 101
    • 63
    • 39
    • 37
    • 34
    • 33
    • 26
    • 21
    • 15
    • 13
    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody reacts with Mr 135 000 PECAM-1 polypeptide from leukocytes and endothelial cells. Detects all endothelial cells in breast. Shows erythroid differentiation in human leukemic cells.
    Immunogen
    Monoclonal antibody to PECAM-1 is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Ulex Europaeus-agglutinin-I reactive glycoproteins from cultured human umbilical vein endothelial cells isolated by lecitin-affinity chromatography were used as immunogen
    Klon
    CE6
    Isotyp
    IgG1
    Top Product
    Discover our top product PECAM1 Primärantikörper
  • Applikationshinweise
    No reactivity with paraffin sections. Working dilution in western blotting is at least 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Lagerung
    4 °C
  • Target
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Andere Bezeichnung
    PECAM-1 (PECAM1 Produkte)
    Hintergrund
    PECAM-1 (CE6) monoclonal antibody against PECAM-1 was produced to characterize human leukemic cells. PECAM-1 is typically an antigen that is shared by both endothelial and distinct hematopoietic cells. It is widely expressed among leukocytes and functions as cell adhesion molecule for these cells. PECAM-1 reactivity can be interpreted as a further evidence for megakaryocytic nature of distinct cell lines has been shown. However, a new useful application for this monoclonal antibody appears to be its very high reactivity against human endothelial cells. A recent review article states that in contrast to other applied endothelial markers, for instance PAL-E monoclonal antibody to endothelial cells and antibodies to factor VIII-related antigen, CE6 monoclonal antibody, reacts with all endothelial cells in human breast.
    Pathways
    Regulation of Actin Filament Polymerization
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