POMC Antikörper (AA 27-235)

Produktnummer ABIN1077682

Produktdetails anti-POMC Antikörper

Target: POMC (Proopiomelanocortin (POMC))

Bindungsspezifität: AA 27-235

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POMC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Polyclonal Antibody to Proopiomelanocortin (POMC)

Spezifität: The antibody is a rabbit polyclonal antibody raised against POMC. It has been selected for its ability to recognize POMC in immunohistochemical staining and western blotting.

Kreuzreaktivität: Ratte

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: RPB311Mu01Recombinant Proopiomelanocortin (POMC)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 500 μg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-POMC Antikörper (ABIN1077682)

Muhsin, Bentley, Bai, Goldsworthy, Cox: "A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 31, Issue 1-2, pp. 17-29, (2020) (PubMed).

Details zu POMC

Target: POMC (Proopiomelanocortin (POMC))

Andere Bezeichnung: POMC (POMC Produkte)

Hintergrund: POC, ProOMC, Pro-OMC, Pro Opiomelanocortin, Corticotropin-lipotropin

Molekulargewicht: 25 kDa

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour