IL-15 Antikörper

Produktnummer ABIN1077441

Dieses Anti-IL-15-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von IL-15 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für IL-15 Antikörper (ABIN1077441)

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser IL-15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL-15 Antikörper

Spezifität: At least two isoforms of IL-15 are known to exist.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 μg/mL.

Kommentare:

(IN) Interleukin-15

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C/-20 °C

Details zu IL-15

Target: IL-15 (IL15) (Interleukin 15 (IL15))

Andere Bezeichnung: IL15

Hintergrund: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.
Synonyms: Interleukin-15, IL15

Molekulargewicht: 18 kDa

Gen-ID: 3600

NCBI Accession: NP_000576

Pathways: JAK-STAT Signalweg, Glycosaminoglycan Metabolic Process