TPT1 Antikörper

Produktnummer ABIN1077430

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch TPT1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für TPT1 Antikörper (ABIN1077430)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser TPT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TPT1 Antikörper

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal TPT1 antibody was raised against a 19 amino acid peptide near the center of human TPT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TPT1 antibody can be used for detection of TPT1 by Western blot at 0.5 - 1 μg/mL.

Kommentare:

(IN) Translationally-controlled tumor protein 1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: 4 °C

Informationen zur Lagerung: TPT1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Haltbarkeit: 12 months

Details zu TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Andere Bezeichnung: TPT1

Hintergrund: TPT1 (translationally controlled tumor protein 1) is a 23 kDa member of the TCTP family of calcium binding proteins. TPT1 is localized in the cytoplasm and widely expressed and serves as a transcriptional activator, calcium transporter, histamine inducer and antiapoptotic caspase 3 inhibitor. TPT1 is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. TPT1 plays a pivotal role in allergic diseases and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
Synonyms: Tumor protein translationally-controlled 1, translationally-controlled tumor protein, TCTP, fortilin, histamine-releasing factor, HRF, p23

Molekulargewicht: 19 kDa (calculated)

Gen-ID: 7178

NCBI Accession: NP_003286

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling