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C3 Antikörper (AA 1580-1592)

Verified C3 Reaktivität: Human ELISA, IHC Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN1049512
  • Target Alle C3 Antikörper anzeigen
    C3 (Complement Component 3 (C3))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1580-1592
    Reaktivität
    • 87
    • 54
    • 34
    • 5
    • 4
    • 4
    • 3
    • 3
    Human
    Wirt
    • 68
    • 42
    • 26
    • 8
    • 7
    • 5
    Ziege
    Klonalität
    • 122
    • 33
    Polyklonal
    Konjugat
    • 65
    • 24
    • 23
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Dieser C3 Antikörper ist unkonjugiert
    Applikation
    • 101
    • 48
    • 37
    • 33
    • 33
    • 29
    • 29
    • 26
    • 22
    • 17
    • 13
    • 12
    • 11
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Verwendungszweck
    complement C3 (aa1580-1592)
    Sequenz
    QQRTFISPIK CRE
    Spezifität
    This antibody is expected to recognize the C3 alpha chain, C3b alpha' chain and the C3c alpha' chain fragment 2.
    Homologie
    Human
    Aufreinigung
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
    Güteklasse
    Verified
    Immunogen
    Peptide with sequence QQRTFISPIKCRE, from the C Terminus of the protein sequence according to NP_000055.2.
    Isotyp
    IgG
    Top Product
    Discover our top product C3 Primärantikörper
  • Applikationshinweise

    DS WB Results: Preliminary experiments gave an approx 125 kDa band in Human Liver lysates after 0.3 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 104 kDa according to the largest fragment C3 alpha chain (aa672-1663). Although this fragment is glycosylated, we have not yet found support in the literature for the observed size. The 125 kDa band was successfully blocked by incubation with the immunizing peptide.

    DS IHC Results: Paraffin embedded Human Placenta and Testis. Recommended concentration: 5 μg/mL.

    Peptide ELISA: antibody detection limit dilution 1:128000.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/mL
    Buffer
    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Minimize freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Target
    C3 (Complement Component 3 (C3))
    Andere Bezeichnung
    Complement Component 3 (C3 Produkte)
    Synonyme
    AHUS5 antikoerper, ARMD9 antikoerper, ASP antikoerper, C3a antikoerper, C3b antikoerper, CPAMD1 antikoerper, AI255234 antikoerper, HSE-MSF antikoerper, Plp antikoerper, C3 antikoerper, C3-1 antikoerper, sb:cb26 antikoerper, si:dkey-76b14.4 antikoerper, wu:fi34b03 antikoerper, wu:fj86e11 antikoerper, C3d antikoerper, asp antikoerper, cpamd1 antikoerper, c3 antikoerper, complement C3 antikoerper, complement component 3 antikoerper, complement component c3a, duplicate 1 antikoerper, complement component 3 L homeolog antikoerper, complement component C3 antikoerper, complement C3-like antikoerper, C3 antikoerper, c3a.1 antikoerper, c3.L antikoerper, LOC443475 antikoerper, c3 antikoerper, c3-1 antikoerper, LOC100060539 antikoerper
    Hintergrund
    C3, complement component 3, AHUS5, ARMD9, ASP, CPAMD1, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, OTTHUMP00000197086, acylation-stimulating protein cleavage product, complement C3, complement component C3
    Gen-ID
    718
    NCBI Accession
    NP_000055
    Pathways
    Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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