LCAT Antikörper (AA 25-433) (FITC)

Produktnummer ABIN1045902

Dieses Anti-LCAT-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LCAT in WB und ELISA. Geeignet für Human.

Kurzübersicht für LCAT Antikörper (AA 25-433) (FITC) (ABIN1045902)

Target: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCAT Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LCAT Antikörper (FITC)

Bindungsspezifität: AA 25-433

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylcholine-sterol acyltransferase protein (25-433AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LCAT

Target: LCAT (Lecithin-Cholesterol Acyltransferase (LCAT))

Andere Bezeichnung: LCAT

Hintergrund:

Background: Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.

Aliases: LCAT antibody, LCAT_HUMAN antibody, Lecithin cholesterol acyltransferase antibody, Lecithin-cholesterol acyltransferase antibody, Phosphatidylcholine sterol acyltransferase antibody, Phosphatidylcholine-sterol acyltransferase antibody, Phospholipid cholesterol acyltransferase antibody, Phospholipid-cholesterol acyltransferase antibody

UniProt: P04180

Pathways: Lipid Metabolism