GABARAPL2 Antikörper (AA 1-117) (FITC)

Produktnummer ABIN1045551

Dieses Anti-GABARAPL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GABARAPL2 in ELISA und WB. Geeignet für Human.

Kurzübersicht für GABARAPL2 Antikörper (AA 1-117) (FITC) (ABIN1045551)

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABARAPL2 Antikörper ist konjugiert mit FITC

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-GABARAPL2 Antikörper (FITC)

Bindungsspezifität: AA 1-117

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Gamma-aminobutyric acid receptor-associated protein-like 2 protein (1-117AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid freeze and thaw cycles. Product is photosensitive and should be protected from light.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Andere Bezeichnung: GABARAPL2

Hintergrund:

Background: Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Aliases: ATG8 antibody, ATG8C antibody, FLC3A antibody, GABA(A) receptor-associated protein-like 2 antibody, Gabarapl2 antibody, Gamma-aminobutyric acid receptor-associated protein-like 2 antibody, Ganglioside expression factor 2 antibody, GATE-16 antibody, GATE16 antibody, GBRL2_HUMAN antibody, GEF-2 antibody, GEF2 antibody, General protein transport factor p16 antibody, Golgi-associated ATPase enhancer of 16 kDa antibody, MAP1 light chain 3-related protein antibody

UniProt: P60520

Pathways: Autophagie