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Interferon gamma Antikörper

Der Kaninchen Polyklonal Anti-Interferon gamma-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Interferon gamma in Proben von Rind (Kuh) zu detektieren. Es sind 2+ Publikationen verfügbar.
Rockland
Produktnummer ABIN1043777
Hersteller Produkt- Nr.: 201-401-c41

Kurzübersicht für Interferon gamma Antikörper (ABIN1043777)

Target

Alle Interferon gamma (IFNG) Antikörper anzeigen
Interferon gamma (IFNG)

Reaktivität

  • 277
  • 104
  • 68
  • 30
  • 29
  • 28
  • 24
  • 22
  • 21
  • 19
  • 18
  • 13
  • 12
  • 11
  • 8
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Rind (Kuh)

Wirt

  • 288
  • 222
  • 48
  • 12
  • 11
  • 4
  • 2
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 345
  • 241
  • 3
Polyklonal

Konjugat

  • 286
  • 99
  • 54
  • 22
  • 20
  • 15
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Interferon gamma Antikörper ist unkonjugiert

Applikation

  • 315
  • 210
  • 186
  • 137
  • 119
  • 119
  • 44
  • 39
  • 36
  • 30
  • 27
  • 25
  • 25
  • 22
  • 20
  • 14
  • 14
  • 14
  • 11
  • 8
  • 7
  • 6
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Hersteller Produkt- Nr.

    201-401-c41

    Hersteller

    Rockland

    Verwendungszweck

    Interferon Gamma Antibody

    Kreuzreaktivität (Details)

    This antibody is specific for bovine IFN gamma protein.

    Produktmerkmale

    Synonyms: rabbit anti-IFN gamma, rabbit anti-Interferon gamma, IFNG, BoIFNG

    Aufreinigung

    This product was protein A purified from monospecific antiserum by chromatography.

    Immunogen

    Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to the 143 amino acids of the mature Bovine IFN Gamma protein.

    Immunogen Type: Recombinant Protein

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: This protein A purified IFN-gamma antibody has been tested by ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 16.9 kDa in size corresponding to bovine IFN gamma by western blotting in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500-1:2,000

    ELISA Dilution: 1:20,000

    Other: User Optimized

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitution Volume: 100 μL

    Reconstitution Buffer: Restore with deionized water (or equivalent)

    Konzentration

    1.59 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • George, Ma, Motyka, Shi, Liu, Griebel: "A dendritic cell-targeted chimeric hepatitis B virus immunotherapeutic vaccine induces both cellular and humoral immune responses in vivo." in: Human vaccines & immunotherapeutics, Vol. 16, Issue 4, pp. 779-792, (2020) (PubMed).

    Schroder, Hertzog, Ravasi, Hume: "Interferon-gamma: an overview of signals, mechanisms and functions." in: Journal of leukocyte biology, Vol. 75, Issue 2, pp. 163-89, (2004) (PubMed).

  • Target

    Interferon gamma (IFNG)

    Andere Bezeichnung

    IFN gamma

    Hintergrund

    Background: Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.

    Gen-ID

    281237

    NCBI Accession

    NP_776511

    UniProt

    A9QXB7

    Pathways

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie
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