DGKA Antikörper

Produktnummer ABIN1042452

Dieses Anti-DGKA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von DGKA in WB und IP. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für DGKA Antikörper (ABIN1042452)

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DGKA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: M6

Produktdetails anti-DGKA Antikörper

Spezifität: M6 is directed against the C-terminal portion (part of the catalytic domain) of rat DGKa.

Produktmerkmale: Other

Aufreinigung: Purified

Anwendungsinformationen

Applikationshinweise: M6 is useful for immunoprecipitation and western blot. Optimal antibody dilution should be determined by titration.

Kommentare:

M6 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with an Escherichia coli cell-expressed, affinity-purified glutathione S-transferase fusion protein of a C-terminal portion (part of the catalytic domain) of rat DGKu.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.09% sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-DGKA Antikörper (ABIN1042452)

Guckes, McCarthy, Brahim: "Use of endosseous implants in a 3-year-old child with ectodermal dysplasia: case report and 5-year follow-up." in: Pediatric dentistry, Vol. 19, Issue 4, pp. 282-5, (1997) (PubMed).

Details zu DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Andere Bezeichnung: DGKa

Hintergrund: Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene. The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Tissue specificity: lymphocytes and oligodendroglial cells. Diacylglycerol kinases are involved in cell signaling, either as regulators of diacylglycerol levels or as intracellular signal-generating enzymes.