The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region. [provided by RefSeq, Jul 2008].
Aktuelle Publikationen für unsere Angiogenin Proteine
Zhang, Rosenberg: "Diversifying selection of the tumor-growth promoter angiogenin in primate evolution." in: Molecular biology and evolution, Vol. 19, Issue 4, pp. 438-45, (2002) (PubMed).
Kurachi, Davie, Strydom, Riordan, Vallee: "Sequence of the cDNA and gene for angiogenin, a human angiogenesis factor." in: Biochemistry, Vol. 24, Issue 20, pp. 5494-9, (1986) (PubMed).
Aliase für Angiogenin Proteine
angiogenin (ANG) Proteine angiogenin, ribonuclease, RNase A family, 5 (Ang) Proteine angiogenin, ribonuclease, RNase A family, 5 (ANG) Proteine angiogenin (Ang) Proteine ribonuclease A family member k6 (RNASE6) Proteine AI385586 Proteine ALS9 Proteine ANG Proteine Ang1 Proteine ANG1 Proteine HEL168 Proteine RNASE4 Proteine RNASE5 Proteine Rnase5 Proteine Rnase5a Proteine