serine/threonine/tyrosine Kinase 1 Proteine (STYK1)

Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen STYK1 Antikörper (94) und STYK1 Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
STYK1 55359 Q6J9G0
STYK1 243659 Q6J9G1
Ratte STYK1 STYK1 500340  
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Top STYK1 Proteine auf

Showing 5 out of 6 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage

STYK1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu serine/threonine/tyrosine Kinase 1 (STYK1) Interaktionspartnern

Human serine/threonine/tyrosine Kinase 1 (STYK1) Interaktionspartner

  1. Overexpression of STYK1 was significantly associated with increased cell proliferation, migratory capability, and invasive capability in vitro, as well as increased volume of tumor, weight of tumor, and number of pulmonary metastasesin hepatocellular carcinoma.

  2. STYK1 plays an important role in glioma development and progression.

  3. Findings show that serine-threonine-tyrosine kinase 1 (NOK) mediates glycolysis and nuclear pyruvate dehydrogenase complex (PDC) associated histone acetylation.

  4. Survival analysis reveals that STYK1 level is an independent prognostic factor for nasopharyngeal carcinoma patients. Our results indicate that STYK1 is a promising therapeutic target in nasopharyngeal carcinoma

  5. Thus, our results reveal a novel tumorigenic function of NOK to mediate the genesis and remodeling of blood and lymphatic vessels during tumor progression.

  6. High STYK1 expression is associated with intrahepatic cholangiocarcinoma.

  7. increased STYK1 protein expression correlates with disease progression and metastasis and may serve as a predictor of poor survival in CRC.

  8. The data indicates that both P203 and V395 residues on NOK are important for NOK mediated mitogenic signaling.

  9. NOK expression increased in renal cell carcinoma and was significantly correlated with TNM stage, Fuhrman grade, poor overall survival, poor disease-free survival, metastasis, and proliferation.

  10. STYK1/NOK is dramatically upregulated in colorectal cancer tissues and could be used as a tumor marker. Furthermore, the high expression of STYK1/NOK is significantly associated with tumor size.

  11. These results suggest that STYK1 is a novel drug resistance factor and could be a predictor of the therapeutic response in acute leukemia.

  12. Our results indicate that NOK expression is of clinical significance and can serve as a prognostic biomarker in non-small cell lung cancer.

  13. SuRTK106/NOK/STYK1 was first identified, classified and shown to have predicted pseudokinase domain.

  14. The expression levels of NOK, p-Akt(Thr308) and p-GSK-3beta(Ser9) were positively correlated in cancerous and non-cancerous breast cell lines.

  15. Taken together, NOK has a strong tendency towards forming aggregates, which may have physiological implications and provide the first evidence that this novel receptor kinase is colocalised with EGFR in endosomes to participate in a post-internalisation step of EGFR.

  16. cloning and characterization; mapped to chromosome 12p13; widely expressed in human tissues

  17. NOK mRNA was highly expressed even at the early clinical stages of the cancer. These results suggest that NOK mRNA might be a new tool to support the diagnosis of lung cancers, irrespective of the clinical stages.

  18. The regulation of STYK1/NOK is achieved independent of ERalpha and suggests further investigation to the relevance of this kinase in breast cancer progression.

  19. results indicate that STYK1/NOK mRNA is widely expressed in the patients with acute leukemia and suggest that inhibition of this molecule could potentially serve as a novel therapeutic target

  20. Overexpression of the potential kinase serine/ threonine/tyrosine kinase 1 (STYK 1) in castration-resistant prostate cancer.

Mouse (Murine) serine/threonine/tyrosine Kinase 1 (STYK1) Interaktionspartner

  1. Point mutations at either Y327 or Y356 dramatically blocked cellular transformation by NOK as examined by colony formation and cellular DNA synthesis.

STYK1 Protein Überblick

Protein Überblick

Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004

Genbezeichner und Symbole assoziert mit STYK1

  • serine/threonine/tyrosine kinase 1 (STYK1)
  • serine/threonine/tyrosine kinase 1 (styk1)
  • serine/threonine/tyrosine kinase 1 (Styk1)
  • 9130025L13 Protein
  • AI326477 Protein
  • Nok Protein
  • RGD1564211 Protein
  • STYK1 Protein
  • SuRTK106 Protein
  • wu:fc39b09 Protein
  • wu:fe11d05 Protein

Bezeichner auf Proteinebene für STYK1

fe11d05 , serine/threonine/tyrosine kinase 1 , tyrosine-protein kinase STYK1-like , novel oncogene with kinase domain , protein PK-unique , tyrosine-protein kinase STYK1 , NOK kinase , mNOK

100063237 Equus caballus
324714 Danio rerio
513920 Bos taurus
100019062 Monodelphis domestica
100170540 Xenopus (Silurana) tropicalis
100344443 Oryctolagus cuniculus
100462028 Pongo abelii
100580273 Nomascus leucogenys
418310 Gallus gallus
55359 Homo sapiens
486689 Canis lupus familiaris
243659 Mus musculus
500340 Rattus norvegicus
100523437 Sus scrofa
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