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Negative regulator of MAP3K1/2 signaling. Zusätzlich bieten wir Ihnen STK38 Antikörper (120) und und viele weitere Produktgruppen zu diesem Protein an.
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Human STK38 Protein expressed in HEK-293 Cells - ABIN2732876
Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages. in Nature communications 2015
Data show that STK38 supports Ras-driven transformation through promoting detachment-induced autophagy.
a novel and intimate link between the protein kinase (zeige CDK7 Proteine) NDR1 (zeige NDRG1 Proteine) and TGFbeta (zeige TGFB1 Proteine) signaling
Data establish STK38 as a conserved regulator of autophagy in human cells and flies.
PLK1-mediated phosphorylation protects the binding of Mob1 to NDR1 and subsequent NDR1 activation
STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.
STK38 regulates MYC (zeige MYC Proteine) protein stability and turnover in a kinase activity-dependent manner. STK38 kinase inactivation abrogates apoptosis following B-cell receptor activation, whereas its silencing significantly decreases MYC (zeige MYC Proteine) levels and increases apoptosis.
cyclin D1 (zeige CCND1 Proteine) has a role in promoting cell cycle progression by enhancing NDR1 (zeige NDRG1 Proteine)/2 kinase activity independent of Cdk4 (zeige CDK4 Proteine)
17-allylamino-17-demethoxygeldanamycin down-regulates STK38, modulating radiosensitivity.
Findings suggest a function of NDR1 (zeige NDRG1 Proteine), which may regulate NF-kappaB (zeige NFKB1 Proteine) activation by its kinase activity.
GSK-3beta inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress
These results revealed that Stk38 kinase catalyzes the phosphorylation of Rbm24 (zeige RBM24 Proteine) during sarcomerogensis and this orchestrates accurate sarcomere alignment.
a novel and intimate link between the protein kinase (zeige CDK7 Proteine) NDR1 and TGFbeta (zeige TGFB1 Proteine) signaling
Stk38 protein kinase (zeige CDK7 Proteine) has a role in inhibiting TLR9 (zeige TLR9 Proteine)-activated inflammatory responses by promoting MEKK2 (zeige MAP3K2 Proteine) ubiquitination in macrophages
Findings show a biological role for MICAL-1 (zeige MICAL1 Proteine) in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.
reduction in the abundances of the NDR proteins NDR1 and NDR2 (zeige STK38L Proteine) results in defective responses to proapoptotic stimuli, thereby facilitating the development of tumors
Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).
NDR1 protein kinase
, Ndr Ser/Thr kinase-like protein
, nuclear Dbf2-related 1
, nuclear Dbf2-related kinase 1
, serine threonine protein kinase
, serine/threonine-protein kinase 38
, nuclear DBF2-related kinase 1