serine/threonine Kinase 38 Proteine (STK38)

Negative regulator of MAP3K1/2 signaling. Zusätzlich bieten wir Ihnen STK38 Antikörper (121) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
STK38 11329 Q15208
STK38 106504 Q91VJ4
Ratte STK38 STK38 361813  
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Top STK38 Proteine auf antikoerper-online.de

Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,626.73
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$547.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,305.50
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Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,305.50
Details
Insektenzellen Human GST tag 5 μg Anmelden zum Anzeigen 11 bis 12 Tage
$506.24
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$346.62
Details
Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$613.69
Details
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 3 bis 4 Tage
$310.00
Details

STK38 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Am meisten referenzierte STK38 Proteine

  1. Human STK38 Protein expressed in HEK-293 Cells - ABIN2732876 : Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages. in Nature communications 2015 (PubMed)

Weitere Proteine zu serine/threonine Kinase 38 (STK38) Interaktionspartnern

Human serine/threonine Kinase 38 (STK38) Interaktionspartner

  1. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop.

  2. Study provides evidence for an inhibitory role of SOCS2 in TNFalpha induced NF-kappa B activation, identifies NDR1 as a novel substrate of SOCS2, and demonstrates that SOCS2 and TNFalpha induced NF-kappa B signaling are linked through NDR1.

  3. Data show that STK38 supports Ras-driven transformation through promoting detachment-induced autophagy.

  4. a novel and intimate link between the protein kinase NDR1 and TGFbeta signaling

  5. Data establish STK38 as a conserved regulator of autophagy in human cells and flies.

  6. PLK1-mediated phosphorylation protects the binding of Mob1 to NDR1 and subsequent NDR1 activation

  7. STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.

  8. STK38 regulates MYC protein stability and turnover in a kinase activity-dependent manner. STK38 kinase inactivation abrogates apoptosis following B-cell receptor activation, whereas its silencing significantly decreases MYC levels and increases apoptosis.

  9. cyclin D1 has a role in promoting cell cycle progression by enhancing NDR1/2 kinase activity independent of Cdk4

  10. 17-allylamino-17-demethoxygeldanamycin down-regulates STK38, modulating radiosensitivity.

  11. Findings suggest a function of NDR1, which may regulate NF-kappaB activation by its kinase activity.

  12. GSK-3beta inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress

  13. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.

  14. These findings establish a novel MST3-NDR-p21 axis as an important regulator of G(1)/S progression of mammalian cells.

  15. Data indicate that human MOB2 is a negative regulator of human NDR kinases in biochemical and biological settings.

  16. NDR1 and NDR2 serine-threonine kinases are regulated by mob proteins

  17. an insert within the catalytic domain between subdomains VII and VIII is autoinhibitory, and the binding of human MOB1 to the N-terminal domain of NDR induces the release of this autoinhibition.

  18. The NDR1 and NDR2 kinases were incorporated into HIV-1 particles and were cleaved by the HIV-1 protease.

  19. In vivo activation of human NDR by membrane-bound hMOBs is dependent on their interaction and occurs solely at the membrane.

  20. These data indicate that NDR-driven centrosome duplication requires Cdk2 activity and that Cdk2-induced centrosome amplification is affected upon reduction of NDR activity.

Mouse (Murine) serine/threonine Kinase 38 (STK38) Interaktionspartner

  1. These results revealed that Stk38 kinase catalyzes the phosphorylation of Rbm24 during sarcomerogensis and this orchestrates accurate sarcomere alignment.

  2. a novel and intimate link between the protein kinase NDR1 and TGFbeta signaling

  3. Stk38 protein kinase has a role in inhibiting TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages

  4. Findings show a biological role for MICAL-1 in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.

  5. reduction in the abundances of the NDR proteins NDR1 and NDR2 results in defective responses to proapoptotic stimuli, thereby facilitating the development of tumors

STK38 Protein Überblick

Protein Überblick

Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).

Genbezeichner und Symbole assoziert mit STK38

  • serine/threonine kinase 38 (STK38)
  • serine/threonine kinase 38 (Stk38)
  • serine/threonine kinase 38 S homeolog (stk38.S)
  • serine/threonine kinase 38b (stk38b)
  • serine/threonine kinase 38a (stk38a)
  • 5830476G13Rik Protein
  • 9530097A09Rik Protein
  • AA617404 Protein
  • NDR Protein
  • Ndr1 Protein
  • si:ch1073-272h17.2 Protein
  • trc Protein
  • wu:fj80h03 Protein
  • zgc:55572 Protein

Bezeichner auf Proteinebene für STK38

NDR1 protein kinase , Ndr Ser/Thr kinase-like protein , nuclear Dbf2-related 1 , nuclear Dbf2-related kinase 1 , serine threonine protein kinase , serine/threonine-protein kinase 38 , nuclear DBF2-related kinase 1 , tricornered , stk38

GENE ID SPEZIES
11329 Homo sapiens
106504 Mus musculus
361813 Rattus norvegicus
380110 Xenopus laevis
533677 Bos taurus
428260 Gallus gallus
481766 Canis lupus familiaris
100063891 Equus caballus
100153410 Sus scrofa
100173048 Pongo abelii
100722460 Cavia porcellus
100332206 Danio rerio
406765 Danio rerio
100346979 Oryctolagus cuniculus
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