serine/threonine Kinase 38 Proteine (STK38)

Negative regulator of MAP3K1/2 signaling.

alle Proteine anzeigen Gen GeneID UniProt
Human STK38 STK38 11329 Q15208
Maus STK38 STK38 106504 Q91VJ4
Ratte STK38 STK38 361813  
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Top STK38 Proteine auf antikoerper-online.de

Showing 10 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$547.80
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,305.50
Details
Hefe Orang-Utan His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,305.50
Details
Insektenzellen Human GST tag   5 μg Anmelden zum Anzeigen 11 bis 12 Tage
$515.20
Details
Baculovirus infected Insect Cells Human GST tag   5 μg Anmelden zum Anzeigen 10 bis 12 Tage
$352.75
Details
Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage
$624.55
Details
Insektenzellen Human GST tag   10 μg Anmelden zum Anzeigen 3 bis 4 Tage
$310.00
Details

Am meisten referenzierte STK38 Proteine

  1. Human STK38 Protein expressed in HEK-293 Cells - ABIN2732876 : Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages. in Nature communications 2015 (PubMed)

Weitere Proteine zu serine/threonine Kinase 38 (STK38) Interaktionspartnern

Human serine/threonine Kinase 38 (STK38) Interaktionspartner

  1. Data show that STK38 supports Ras-driven transformation through promoting detachment-induced autophagy.

  2. a novel and intimate link between the protein kinase (zeige CDK7 Proteine) NDR1 (zeige NDRG1 Proteine) and TGFbeta (zeige TGFB1 Proteine) signaling

  3. Data establish STK38 as a conserved regulator of autophagy in human cells and flies.

  4. PLK1-mediated phosphorylation protects the binding of Mob1 to NDR1 and subsequent NDR1 activation

  5. STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.

  6. STK38 regulates MYC (zeige MYC Proteine) protein stability and turnover in a kinase activity-dependent manner. STK38 kinase inactivation abrogates apoptosis following B-cell receptor activation, whereas its silencing significantly decreases MYC (zeige MYC Proteine) levels and increases apoptosis.

  7. cyclin D1 (zeige CCND1 Proteine) has a role in promoting cell cycle progression by enhancing NDR1 (zeige NDRG1 Proteine)/2 kinase activity independent of Cdk4 (zeige CDK4 Proteine)

  8. 17-allylamino-17-demethoxygeldanamycin down-regulates STK38, modulating radiosensitivity.

  9. Findings suggest a function of NDR1 (zeige NDRG1 Proteine), which may regulate NF-kappaB (zeige NFKB1 Proteine) activation by its kinase activity.

  10. GSK-3beta inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress

Mouse (Murine) serine/threonine Kinase 38 (STK38) Interaktionspartner

  1. a novel and intimate link between the protein kinase (zeige CDK7 Proteine) NDR1 and TGFbeta (zeige TGFB1 Proteine) signaling

  2. Stk38 protein kinase (zeige CDK7 Proteine) has a role in inhibiting TLR9 (zeige TLR9 Proteine)-activated inflammatory responses by promoting MEKK2 (zeige MAP3K2 Proteine) ubiquitination in macrophages

  3. Findings show a biological role for MICAL-1 (zeige MICAL1 Proteine) in apoptosis and define a novel negative regulatory mechanism of MST-NDR signaling.

  4. reduction in the abundances of the NDR proteins NDR1 and NDR2 (zeige STK38L Proteine) results in defective responses to proapoptotic stimuli, thereby facilitating the development of tumors

STK38 Protein Überblick

Protein Überblick

Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).

Genbezeichner und Symbole assoziert mit STK38

  • serine/threonine kinase 38 (STK38)
  • serine/threonine kinase 38 S homeolog (stk38.S)
  • serine/threonine kinase 38 (Stk38)
  • serine/threonine kinase 38b (stk38b)
  • 5830476G13Rik Protein
  • 9530097A09Rik Protein
  • AA617404 Protein
  • NDR Protein
  • Ndr1 Protein
  • si:ch1073-272h17.2 Protein
  • trc Protein

Bezeichner auf Proteinebene für STK38

nuclear DBF2-related kinase 1 , tricornered , NDR1 protein kinase , Ndr Ser/Thr kinase-like protein , nuclear Dbf2-related 1 , nuclear Dbf2-related kinase 1 , serine threonine protein kinase , serine/threonine-protein kinase 38 , stk38

GENE ID SPEZIES
100063891 Equus caballus
380110 Xenopus laevis
428260 Gallus gallus
11329 Homo sapiens
481766 Canis lupus familiaris
533677 Bos taurus
106504 Mus musculus
361813 Rattus norvegicus
100153410 Sus scrofa
100722460 Cavia porcellus
100173048 Pongo abelii
100332206 Danio rerio
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