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RHO GTPases (see ARHA\; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003 [PubMed 12650940]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen ARHGAP15 Antikörper (27) und und viele weitere Produktgruppen zu diesem Protein an.
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ARHGAP15 immunoreactivity correlated with decreased risk of recurrence and improved prognosis in breast carcinoma. ARHGA15 overexpression suppressed cell proliferation and migration of MCF-7 cells.
FOXP3 can regulate the expression of ARHGAP15 and affects migration of glioma cells through the Rac1 signaling pathway
ArhGAP15 plays a dual negative role in regulating small GTPase signaling, by acting at the level of the GTPase itself, as well interacting with its effector, Pak kinase.
ARHGAP15 is associated with acute lung injury in mice
a potential regulator of Rac1
ArhGAP15 role in the modulation of Rac1/Rac3 activity in the hippocampal inhibitory neurons.
these results demonstrate the relevance of ArhGAP15 in the selective regulation of multiple neutrophil functions
Arhgap15 is associated with acute lung injury
Performed mutational analysis on exon 9 of Asian, African and European cattle ARHGAP15, a strong candidate for cattle trypanotolerance on BTA2.
RHO GTPases (see ARHA\; MIM 165390) regulate diverse biologic processes, and their activity is regulated by RHO GTPase-activating proteins (GAPs), such as ARHGAP15 (Seoh et al., 2003
Rho GTPase activating protein 15
, polymorphic marker clone XE09
, Rho GTPase activating protein 27
, SH3 domain containing 20
, rho GTPase-activating protein 15-like
, rho GTPase-activating protein 15
, rho-type GTPase-activating protein 15