anti-phosphofructokinase, Platelet (PFKP) Antikörper

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC Zusätzlich bieten wir Ihnen PFKP Kits (41) und PFKP Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PFKP 5214 Q01813
PFKP 56421 Q9WUA3
PFKP 60416 P47860
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Top anti-PFKP Antikörper auf

Showing 10 out of 119 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Maus Unkonjugiert FACS, IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
Human Maus Unkonjugiert FACS, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert IHC (p), WB Fibroblasts were cultured for 2 d in DMEM supplemented with 10% TH-depleted bovine serum. They were then treated with 2 nM T3 in the absence or presence of either LY294002 (LY, 50 M) or PD98059 (PD, 50 M), added 1 h before the addition of T3. Cells were harvested 24 h after T3 treatment. Whole-cell lysates, obtained from two separately treated culture dishes for each treatment, were subjected to WB with anti-PFKP. (Mol. Endocrinol. 2005 Dec 01.19(12):2955-2963) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Maus Unkonjugiert FACS, IF, IHC, IHC (p), WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of PFKP staining in NIH3T3 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of PFKP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Maus Unkonjugiert FACS, ICC, IF, IHC, IHC (p), WB Flow Cytometry: PFKP Antibody (1D6) [NBP2-01539] - Analysis of Jurkat cells, using anti-PFKP antibody, (Red), compared to a nonspecific negative control antibody (Blue). Immunocytochemistry/Immunofluorescence: PFKP Antibody (1D6) [NBP2-01539] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY PFKP. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human A549 Cells; Lane2: Porcine Heart Tissue; Lane3: Human Jurkat Cells; Lane4: Porcine Skeletal Muscle Tissue. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of Phospho-PFKP(Y52) expression in various lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage

Am meisten referenzierte anti-PFKP Antikörper

  1. Human Polyclonal PFKP Primary Antibody für IHC (p), WB - ABIN392744 : Moeller, Dumitrescu, Refetoff: Cytosolic action of thyroid hormone leads to induction of hypoxia-inducible factor-1alpha and glycolytic genes. in Molecular endocrinology (Baltimore, Md.) 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PFKP Primary Antibody für IHC (p), ELISA - ABIN544922 : Morrison, Simpson, Fothergill-Gilmore, Boyd, Connor: Regional chromosomal assignment of the human platelet phosphofructokinase gene to 10p15. in Human genetics 1992 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen PFKP Interaktionspartner

Human phosphofructokinase, Platelet (PFKP) Interaktionspartner

  1. Snail functions as a metabolic switch between aerobic glycolysis and pentose phosphate pathway by repressing PFKP, a cancer-specific PFK-1, allowing cancer cell survival under metabolic stress.

  2. Here the authors show that PFK1 platelet isoform is upregulated in Glioblastoma and is required for tumor growth mechanistically, such upregulation is due to an increased stability induced by AKT activation via phosphorylation on residue S386.

  3. Data indicate that platelet isoform of phosphofructokinase (PFKP) not only is required for metabolic reprogramming and maintaining cell proliferation, but also may be a valid target for anti-renal cancer pharmaceutical agents.

  4. The crystallized PFKP is permanently activated by a deletion of the 22 C-terminal residues.

  5. Anti-human protein S antibody induces tissue factor expression through a direct interaction with PFKP and ERK1/2 activation in coronary artery endothelial cells.

  6. expression of TARDBP is significantly elevated in HCC and it regulates the expression of PFKP, the rate-limiting enzyme for glycolysis, through negative regulation of microRNA 520s (miR-520s).

  7. KLF4 plays a role in maintenance of high glycolytic metabolism by transcriptional activation of the PFKP gene in breast cancer cells.

  8. PFKP was identified using a trifunctional phenyl sulfonate probe.

  9. The transcription start point was determined at 48 bp upstream of the start codon. the region -65 to +48 turned out to be sufficient for promoter activity

  10. Two phosphofructokinase (PFK) chimeras were constructed by exchanging the N- and C-terminal halves of the mammalian M- and C-type isozymes.

  11. PFKP polymorphisms play no apparent role in the development of common forms of obesity in the Danish population.

PFKP Antigen-Profil

Protein Überblick

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM\; MIM 610681) and liver (PFKL\; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981)

Genbezeichner und Symbole assoziert mit PFKP

  • phosphofructokinase, platelet (pfkp) Antikörper
  • phosphofructokinase, platelet (PFKP) Antikörper
  • phosphofructokinase, platelet S homeolog (pfkp.S) Antikörper
  • ATP-dependent 6-phosphofructokinase, platelet type (LOC100549777) Antikörper
  • phosphofructokinase, platelet (Pfkp) Antikörper
  • 1200015H23Rik Antikörper
  • 9330125N24Rik Antikörper
  • pfk Antikörper
  • PFK-C Antikörper
  • PFKF Antikörper
  • PFKM Antikörper
  • PFKP Antikörper

Bezeichner auf Proteinebene für PFKP

phosphofructokinase, platelet , 6-phosphofructokinase type C , PFK-C , phosphofructo-1-kinase isozyme C , phosphofructokinase 1 , phosphohexokinase , 6-phosphofructokinase, platelet type , Phosphofructokinase, platelet type , ATP:D-fructose 6-phosphate 1-phosphotransferase , 6-phosphofructo-1-kinase, C-type , phosphofructokinase C isozyme , phosphofructokinase, muscle

394825 Xenopus (Silurana) tropicalis
450266 Pan troglodytes
100022041 Monodelphis domestica
100037146 Xenopus laevis
100070818 Equus caballus
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100229947 Taeniopygia guttata
100549777 Meleagris gallopavo
100561110 Anolis carolinensis
100601116 Nomascus leucogenys
5214 Homo sapiens
56421 Mus musculus
60416 Rattus norvegicus
100009526 Oryctolagus cuniculus
100722738 Cavia porcellus
100521394 Sus scrofa
478019 Canis lupus familiaris
507119 Bos taurus
428411 Gallus gallus
101108592 Ovis aries
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