anti-Zinc Finger and BTB Domain Containing 33 (ZBTB33) Antikörper

ZBTB33 encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. Zusätzlich bieten wir Ihnen ZBTB33 Proteine (4) und ZBTB33 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ZBTB33 10009 Q86T24
ZBTB33 56805 Q8BN78
ZBTB33 501506  
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Top anti-ZBTB33 Antikörper auf

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ZBTB33 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-ZBTB33 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: Kaiso Antibody [NBP1-87866] - Staining of human breast shows moderate nuclear positivity in glandular cells. Immunocytochemistry/Immunofluorescence: Kaiso Antibody [NBP1-87866] Staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli, plasma membrane & cytoplasm. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Maus Unkonjugiert WB Western Blot analysis of ZBTB33 expression in transfected 293T cell line by ZBTB33 monoclonal antibody (M01), clone 2B2. Lane 1: ZBTB33 transfected lysate(74.6 KDa). Lane 2: Non-transfected lysate. Western blot analysis of ZBTB33 over-expressed 293 cell line, cotransfected with ZBTB33 Validated Chimera RNAi used as specificity and loading control. 0.05 mg Anmelden zum Anzeigen 8 bis 11 Tage
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB Human Small Intestine, Vessel (formalin-fixed, paraffin-embedded) stained with ZBTB33 antibody ABIN213733 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
Maus Maus Unkonjugiert WB Kaiso mAb (Clone 6F1D) tested by Western blot. Nuclear extract of CSML0 cells (20 µg) was probed with Kaiso mAb (Clone 6F1D) (1 µg/ml dilution). 200 μg Anmelden zum Anzeigen 1 bis 2 Tage
Human Kaninchen Unkonjugiert WB Western Blot: Kaiso Antibody [NBP1-80316] - HepG2 cell lysate, concentration 0.2-1 ug/ml. 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
Huhn Maus Unkonjugiert IP, IHC, WB   200 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert WB ZBTB33 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
Hund Maus Unkonjugiert MA, WB   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage

ZBTB33 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human , ,
, ,
Mouse (Murine) ,
Rat (Rattus) ,

Am meisten referenzierte anti-ZBTB33 Antikörper

  1. Human Polyclonal ZBTB33 Primary Antibody für ICC, IF - ABIN4328014 : Zhang, Gallup, Zlock, Feeling Chen, Finkbeiner, McNamara: Cigarette Smoke Mediates Nuclear to Cytoplasmic Trafficking of Transcriptional Inhibitor Kaiso through MUC1 and P120-Catenin. in The American journal of pathology 2016 (PubMed)

Weitere Antikörper gegen ZBTB33 Interaktionspartner

Xenopus laevis Zinc Finger and BTB Domain Containing 33 (ZBTB33) Interaktionspartner

  1. Dyrk1A (zeige DYRK1A Antikörper) positively and selectively modulates p120-catenin (zeige CTNND1 Antikörper) protein levels, thus having an impact on p120-catenin (zeige CTNND1 Antikörper) and Kaiso (and canonical Wnt (zeige WNT2 Antikörper)) gene targets such as siamois and wnt11.

  2. xKaiso plays an essential role as a global repressor of methylated genes during early vertebrate development.

  3. propose that mutual inhibition by Kaiso/TCF3 (zeige TCF3 Antikörper) of their DNA-binding functions may be important in developmental or cancer contexts and acts as a regulatory node that integrates epigenetic and Wnt (zeige WNT2 Antikörper) signalling pathways

  4. The major phenotypic defects associated with xKaiso depletion are premature transcription activation before the mid-blastula transition and concomitant activation of a p53 (zeige TP53 Antikörper)-dependent cell-death pathway

  5. Kaiso is a bimodal modulator for Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling.

Human Zinc Finger and BTB Domain Containing 33 (ZBTB33) Interaktionspartner

  1. A role for Kaiso in the proliferation.

  2. Suggest a role for Kaiso in the progression of pancreatic ductal adenocarcinomas, involving the epithelial mesenchymal transformation markers, E-cadherin (zeige CDH1 Antikörper) and Zeb1 (zeige ZEB1 Antikörper).

  3. a novel mechanism by which ZBTB33 mediates the cyclin D1 (zeige CCND1 Antikörper)/cyclin E1 (zeige CCNE1 Antikörper)/RB1 (zeige RB1 Antikörper)/E2F (zeige E2F1 Antikörper) pathway, controlling passage through the G1 restriction point and accelerating cancer cell proliferation.

  4. GR is a putative target gene of Kaiso.

  5. Kaiso high expression correlated with invasion of prostate cancer.

  6. Results show that Kaiso binding to unmethylated Kaiso binding site in the human ICR1 is necessary for ICR1 methylation maintenance and affects transcription rates of the lncRNA H19 (zeige NCKAP1 Antikörper).

  7. Kaiso modulates HIF1A (zeige HIF1A Antikörper) gene expression by binding to the methylated HIF1A (zeige HIF1A Antikörper) promoter in a region proximal to the autoregulatory HIF-1 (zeige HIF1A Antikörper) binding site, primarily during hypoxia.

  8. NF-kappaB (zeige NFKB1 Antikörper) response element, located close to the p53RE#1, mediates APAF1 (zeige APAF1 Antikörper) transcriptional repression by affecting interaction between KAISO and p53 (zeige TP53 Antikörper)

  9. KAISO is a regulator of p53 (zeige TP53 Antikörper)-mediated transcription of CDKN1A and apoptotic genes

  10. Data indicate that Kaiso protein participates in the regulation of beta-catenin (zeige CTNNB1 Antikörper) mRNA expression by interacting with p120-catenin (zeige CTNND1 Antikörper) in the lung cancer cell lines.

Mouse (Murine) Zinc Finger and BTB Domain Containing 33 (ZBTB33) Interaktionspartner

  1. We also demonstrate that Kaiso inhibits Znf131 (zeige ZNF131 Antikörper) expression, raising the possibility that Kaiso and Znf131 (zeige ZNF131 Antikörper) act to fine-tune target gene expression. Together, our findings implicate Znf131 (zeige ZNF131 Antikörper) as a co-regulator of Kaiso-mediated biological processes.

  2. Kaiso and Sox10 (zeige SOX10 Antikörper) sequentially interact with Tcf7l2 (zeige TCF7L2 Antikörper) to coordinate the maturation of oligodendrocyte.

  3. Study revealed the involvement of the Zbtb33 gene and, probably, the Kaiso protein in the regulation of locomotion and brain morphology in mice

  4. a mechanistic link between E-cadherin (zeige CDH1 Antikörper) loss and subsequent control of Rho-driven anoikis resistance through p120 (zeige CTNND1 Antikörper)- and Kaiso-dependent expression of Wnt11 (zeige WNT11 Antikörper), is reported.

  5. S100A3 (zeige S100A3 Antikörper) is a new target gene of Kaiso in mouse skin

  6. ZBTB33 expression may elicit intestinal inflammation by antagonizing p120ctn (zeige CTNND1 Antikörper) function.

  7. derepressed Bcl6 (zeige BCL6 Antikörper) expression may be responsible for increases in germinal centers cell proliferation and splenomegaly of Kaiso knockout mice.

  8. KAISO, similar to SMRT, accelerates the cell cycle and increases fat accumulation upon knockdown, identifying KAISO as an adipogenic repressor that likely modulates the mitotic clonal expansion phase of this process.

  9. Znf131 (zeige ZNF131 Antikörper) is a transcriptional activator, a less common function of POZ-ZF proteins, that is negatively regulated by its heterodimerization partner Kaiso.

  10. These results provide the first experimental evidence that rapsyn (zeige RAPSN Antikörper) is a direct sequence-specific target of Kaiso and delta-catenin (zeige CTNND2 Antikörper).

ZBTB33 Antigen-Profil

Protein Überblick

This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.

Genbezeichner und Symbole assoziert mit ZBTB33

  • zinc finger and BTB domain containing 33 S homeolog (zbtb33.S) Antikörper
  • zinc finger and BTB domain containing 33 (ZBTB33) Antikörper
  • zinc finger and BTB domain containing 33 (Zbtb33) Antikörper
  • AW260253 Antikörper
  • E130014G12Rik Antikörper
  • Kaiso Antikörper
  • RGD1566309 Antikörper
  • Znf-kaiso Antikörper
  • ZNF348 Antikörper

Bezeichner auf Proteinebene für ZBTB33

DNA-methylation dependent transcriptional repressor Kaiso-like protein , transcriptional regulator Kaiso , xKaiso , zinc finger and BTB domain-containing protein 33 , WUGSC:H_DJ525N14.1 , kaiso transcription factor , zinc finger transcription factor Kaiso , Kaiso

398248 Xenopus laevis
10009 Homo sapiens
100685062 Canis lupus familiaris
784871 Bos taurus
56805 Mus musculus
501506 Rattus norvegicus
422367 Gallus gallus
Ausgewählte Anbieter für anti-ZBTB33 (ZBTB33) Antikörper
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