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Plays a role in transport between endoplasmic reticulum and Golgi (By similarity). Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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The swine YIPF5 gene was moderately expressed in fat and spleen, and hardly expressed in small intestine, large intestine, liver, lung, muscle and kidney.
The significance of YIPF5 protein for the maintenance of the morphology of the Golgi was tested by RNA interference, revealing a number of specific morphological changes to this organelle on their depletion.
we propose a model for intracellular Brucella replication that exploits the host unfolded protein response and endoplasmic reticulum -derived vacuole formation machineries, both of which depend on Yip1A-mediated IRE1 activation.
Findings suggest that the ability of Yip1A to bind its established binding partners may be uncoupled from its ability to control ER whorl formation.
Results reveal a conserved Yip1A-mediated mechanism for ER membrane organization that may serve to regulate cargo exit from the organelle.
The highest level of expression was found in coronary smooth muscle cells, in which expression of the SMAP-5 gene was induced by transforming growth factor beta1, thus indicating that this protein may play an important role in inflammation.
Human Yip1A (YIPF5) interacts with and localizes human Yif1 (YIF1A) to the Golgi apparatus.
YIPF5 is not restricted to Endoplasmic Reticulum exit sites but also localized in the ER-Golgi intermediate compartment (ERGIC) and some in the cis-Golgi at steady state
These results suggested that Yip1A has a role in COPI-independent retrograde transport from the Golgi to the ER and regulates the membrane recruitment of Rab6.
Plays a role in transport between endoplasmic reticulum and Golgi (By similarity).
, YIP1 family member 5
, golgi membrane protein SB140
, Yip1 domain family, member 5
, smooth muscle cell associated protein 5
, YPT-interacting protein 1 A
, five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 5
, smooth muscle cell-associated protein 5