anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Antikörper

Vitamin K is essential for blood clotting but must be enzymatically activated. Zusätzlich bieten wir Ihnen VKORC1 Kits (17) und VKORC1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Gen	GeneID	UniProt
VKORC1	79001	Q9BQB6
VKORC1	27973	Q9CRC0
VKORC1	309004	Q6TEK4

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Top anti-VKORC1 Antikörper auf antikoerper-online.de

Showing 10 out of 29 products:

Katalog Nr.	Reaktivität	Wirt	Konjugat	Applikation	Menge	Anbieter	Lieferzeit	Preis	Details
ABIN2789450	Rind (Kuh)	Kaninchen	Unkonjugiert	IHC, WB	100 μL	Anmelden zum Anzeigen	2 bis 3 Tage	$289.00	Details
ABIN652040	Human	Kaninchen	Unkonjugiert	IHC (p), WB	400 μL	Anmelden zum Anzeigen	10 bis 11 Tage	$335.50	Details
ABIN1494985	Fledermaus	Kaninchen	Unkonjugiert	IHC, WB	50 μg	Anmelden zum Anzeigen	7 bis 9 Tage	$551.83	Details
ABIN5556597	Human	Kaninchen	Unkonjugiert	EIA, IF, IHC (p), WB	0.1 mg	Anmelden zum Anzeigen	8 bis 11 Tage	$474.10	Details
ABIN1031658	Human	Kaninchen	Unkonjugiert	ELISA, WB	0.1 mg	Anmelden zum Anzeigen	2 bis 3 Tage	$350.00	Details
ABIN1105001	Human	Kaninchen	Unkonjugiert	IHC, WB	100 μg	Anmelden zum Anzeigen	7 bis 9 Tage	$551.83	Details
ABIN2385766	Human	Kaninchen	Unkonjugiert	IHC, ELISA, WB	200 μL	Anmelden zum Anzeigen	11 bis 16 Tage	$594.00	Details
ABIN1947957	Human	Kaninchen	APC	IHC, ELISA, WB	200 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$1,013.83	Details
ABIN1947958	Human	Kaninchen	Biotin	IHC, ELISA, WB	200 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$1,013.83	Details
ABIN1947959	Human	Kaninchen	FITC	IHC, ELISA, WB	200 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$1,013.83	Details

VKORC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute	Applikationen	Konjugat
Human	,	, , , , ,
Mouse (Murine)		,
Rat (Rattus)		,

Weitere Produktkategorien zu VKORC1 Antikörper

Weitere Antikörper gegen VKORC1 Interaktionspartner

Human Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Interaktionspartner

The plasma S-warfarin (Cp(S)) time courses following the genotype-based dosing algorithms simulated using the PPK (zeige GJB2 Antikörper) estimates showed African Americans with CYP2C9 (zeige CYP2C9 Antikörper)*1/*1 and any of the VKORC1 genotypes would have an average Cp(S) at steady state 1.5-1.8 times higher than in Asians and whites.
The final regression models for White and Black patients (Fig. 1) included age, weight, prosthetic valves, amiodarone use, CYP2C9 (zeige CYP2C9 Antikörper)*3, and VKORC1 3673 G>A genotypes as covariates, whereas possession of CYP2C9 (zeige CYP2C9 Antikörper)*2 and simvastatin use were retained in the final model for White, but not Black patients.
No relationship between VKORC1 variants and clinical outcomes in elderly patients treated with vitamin K antagonists.
Until the age of 19, weight has a far greater effect on Vitamin K antagonist dosing variation than VKORC1 and CYP2C9 (zeige CYP2C9 Antikörper) polymorphisms. During the age of 20-40years, VKORC1 and CYP2C9 (zeige CYP2C9 Antikörper) polymorphisms play a significant role.
The VKORC1: c.-1639 G>A polymorphism is associated with aneurysms of the ascending aorta.
1639G4A polymorphism of the vitamin K epoxide reductase complex subunit 1 gene (VKORC1) is likely to be a new risk factor of Retinal Vascular Occlusion.
Studied the association of CYP2C9 (zeige CYP2C9 Antikörper)*2 (430C/T), *3 (1075A/C) and VKORC1 (-1639G/A) polymorphisms on warfarin dose requirements in patients post cardiac valve surgery. Found age and presence of CYP2C9 (zeige CYP2C9 Antikörper) *2 allele significantly affect the daily dosage of warfarin during initiation of warfarin therapy after cardiac valve replacement surgery.
The expression of VKOR in benign prostate epithelial cells, along with the association between a functional VKOR SNP and prostate cancer risk, suggests a possible role for VKOR in mediating the effect of warfarin on prostate cancer risk.
analysis of VKORC1 AA-CYP2C9 (zeige CYP2C9 Antikörper)*1*1 genotypes reveals dosing algorithms for vitamin K antagonists
VKORC1 genotype influenced the likelihood of INR (zeige INSR Antikörper) lability during warfarin maintenance in atrial fibrillation patients.

Mouse (Murine) Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Interaktionspartner

quantified mRNA levels for VKORC1, VKORC1L1 (zeige VKORC1L1 Antikörper), GGCX (zeige GGCX Antikörper), and NQO1 (zeige NQO1 Antikörper) and measured VKOR enzymatic activities in 29 different tissues
OCN is gamma-carboxylated by the gamma-carboxylase (GGCX (zeige GGCX Antikörper)) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1.
The involvement of VKORC1L1 (zeige VKORC1L1 Antikörper) in VKOR activity partly explains the low susceptibility of some extrahepatic tissues to vitamin K antagonists.
molecular cloning [VKORC1]
The genetic basis for resistance to anticoagulants lies in mutations in Vkorc1.
An analysis of novel mutations show that the VKORC1 gene is the main target for spontaneous mutations conferring warfarin resistance.
Each VKORC1 T-allele present in patients from the Rotterdam anticoagulation therapy study is shown to decrease the required acenocoumarol dosage by 5.1 mg/week.

VKORC1 Antigen-Profil

Protein Überblick

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit VKORC1

vitamin K epoxide reductase complex, subunit 1 (VKORC1) Antikörper
vitamin K epoxide reductase complex subunit 1 (vkorc1) Antikörper
vitamin K epoxide reductase complex, subunit 1 (vkorc1) Antikörper
vitamin K epoxide reductase complex subunit 1 (VKORC1) Antikörper
Vitamin-K epoxide reductase (Vkor) Antikörper
vitamin K epoxide reductase complex, subunit 1 (Vkorc1) Antikörper

BP1071 Antikörper
CG33544 Antikörper
D7Wsu86e Antikörper
Dmel\\CG33544 Antikörper
EDTP308 Antikörper
HDC06808 Antikörper
IMAGE3455200 Antikörper
MGC89620 Antikörper
MST134 Antikörper
MST576 Antikörper
VKCFD2 Antikörper
VKOR Antikörper
VKORC1 Antikörper

Bezeichner auf Proteinebene für VKORC1

phylloquinone epoxide reductase , vitamin K1 epoxide reductase (warfarin-sensitive) , vitamin K epoxide reductase complex, subunit 1 , CG33544-PA , Vkor-PA , vitamin K dependent clotting factors deficiency 2 , vitamin K epoxide reductase complex subunit 1 , vitamin K1 2,3-epoxide reductase subunit 1 , Warfarin resistance

GENE ID	SPEZIES
404205	Gallus gallus
446034	Takifugu rubripes
448775	Xenopus (Silurana) tropicalis
479775	Canis lupus familiaris
3346188	Drosophila melanogaster
79001	Homo sapiens
27973	Mus musculus
309004	Rattus norvegicus
445422	Bos taurus

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