anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Antikörper

Vitamin K is essential for blood clotting but must be enzymatically activated. Zusätzlich bieten wir Ihnen VKORC1 Kits (14) und VKORC1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
VKORC1 79001 Q9BQB6
VKORC1 27973 Q9CRC0
VKORC1 309004 Q6TEK4
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Top anti-VKORC1 Antikörper auf antikoerper-online.de

Showing 10 out of 28 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Rabbit Anti-VKORC1 Antibody Catalog Number: ARP63330_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-VKORC1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB VKORC1 Antibody (N-term) (ABIN652040) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the VKORC1 antibody detected the VKORC1 protein (arrow). VKORC1 Antibody (N-term) (ABIN652040) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Kaninchen Unkonjugiert IHC, WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details
Human Kaninchen Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
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Human Kaninchen APC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
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Human Kaninchen FITC IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details
Human Kaninchen Biotin IHC, ELISA, WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$1,013.83
Details

VKORC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human ,


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Mouse (Murine)


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Rat (Rattus)


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Weitere Antikörper gegen VKORC1 Interaktionspartner

Human Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Interaktionspartner

  1. analysis of VKORC1 AA-CYP2C9 (zeige CYP2C9 Antikörper)*1*1 genotypes reveals dosing algorithms for vitamin K antagonists

  2. VKORC1 genotype influenced the likelihood of INR (zeige INSR Antikörper) lability during warfarin maintenance in atrial fibrillation patients.

  3. results suggest that the VKORC1 gene rs7294 polymorphism is important for the development of essential hypertension

  4. both vIL (zeige VIL1 Antikörper)-6 and VKORC1v2 interact with calnexin (zeige CANX Antikörper) cycle proteins UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1 (zeige UGGT1 Antikörper)), which catalyzes monoglucosylation of N-glycans, and oppositely acting glucosidase II (GlucII), and that vIL (zeige VIL1 Antikörper)-6 can promote protein folding.

  5. Patients with non-variceal upper gastrointestinal bleeding caused by the use of NSAID or low dose aspirin are more frequent carriers of the VKORC1-1639 G>A polymorphism.

  6. Our results supported an enzyme activating role for rs56314408C of VKORC1 while rs9923231G>A had no evidence of being functional

  7. Polymorphisms in VKORC1 partially affected daily warfarin dosage requirements. VKORC1 genotype and height are the primary determinants influencing warfarin dosage in Japanese pediatric patients.

  8. VKORC polymorphism affects PC dosage in the initiation as well as the maintenance phase. High rates of bleeding complications and thromboembolic events were found at the beginning of PC therapy in VAD (zeige KCTD1 Antikörper) patients.

  9. Genetic variants of CYP2C9 (zeige CYP2C9 Antikörper)/VKORC1 and age are significant determinants of the maintenance dose of warfarin in patients with atrial fibrillation/valve replacement.

  10. The Arg98Trp mutation disrupts an ER retention motif of VKORC1 leading to mislocalisation of the protein to outside the endoplasmatic reticulum. In this review, we summarize the clinical data, diagnosis, therapy and molecular pathomechanism of VKCFD2.

Mouse (Murine) Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Interaktionspartner

  1. quantified mRNA levels for VKORC1, VKORC1L1, GGCX (zeige GGCX Antikörper), and NQO1 (zeige NQO1 Antikörper) and measured VKOR enzymatic activities in 29 different tissues

  2. OCN is gamma-carboxylated by the gamma-carboxylase (GGCX (zeige GGCX Antikörper)) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1.

  3. The involvement of VKORC1L1 in VKOR activity partly explains the low susceptibility of some extrahepatic tissues to vitamin K antagonists.

  4. molecular cloning [VKORC1]

  5. The genetic basis for resistance to anticoagulants lies in mutations in Vkorc1.

  6. An analysis of novel mutations show that the VKORC1 gene is the main target for spontaneous mutations conferring warfarin resistance.

  7. Each VKORC1 T-allele present in patients from the Rotterdam anticoagulation therapy study is shown to decrease the required acenocoumarol dosage by 5.1 mg/week.

VKORC1 Antigen-Profil

Protein Überblick

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit VKORC1

  • vitamin K epoxide reductase complex, subunit 1 (VKORC1) Antikörper
  • vitamin K epoxide reductase complex subunit 1 (vkorc1) Antikörper
  • vitamin K epoxide reductase complex, subunit 1 (vkorc1) Antikörper
  • vitamin K epoxide reductase complex subunit 1 (VKORC1) Antikörper
  • Vitamin-K epoxide reductase (Vkor) Antikörper
  • vitamin K epoxide reductase complex, subunit 1 (Vkorc1) Antikörper
  • BP1071 Antikörper
  • CG33544 Antikörper
  • D7Wsu86e Antikörper
  • Dmel\\CG33544 Antikörper
  • EDTP308 Antikörper
  • HDC06808 Antikörper
  • IMAGE3455200 Antikörper
  • MGC89620 Antikörper
  • MST134 Antikörper
  • MST576 Antikörper
  • VKCFD2 Antikörper
  • VKOR Antikörper
  • VKORC1 Antikörper

Bezeichner auf Proteinebene für VKORC1

phylloquinone epoxide reductase , vitamin K1 epoxide reductase (warfarin-sensitive) , vitamin K epoxide reductase complex, subunit 1 , CG33544-PA , Vkor-PA , vitamin K dependent clotting factors deficiency 2 , vitamin K epoxide reductase complex subunit 1 , vitamin K1 2,3-epoxide reductase subunit 1 , Warfarin resistance

GENE ID SPEZIES
404205 Gallus gallus
446034 Takifugu rubripes
448775 Xenopus (Silurana) tropicalis
479775 Canis lupus familiaris
3346188 Drosophila melanogaster
79001 Homo sapiens
27973 Mus musculus
309004 Rattus norvegicus
445422 Bos taurus
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