VKORC1 Antikörper (N-Term)

Produktnummer ABIN6991675

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VKORC1 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für VKORC1 Antikörper (N-Term) (ABIN6991675)

Target: VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VKORC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-VKORC1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: VKORC1 Antibody is affinity chromatography purified via peptide column.

Immunogen: VKORC1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human VKORC1. The immunogen is located within the first 50 amino acids of VKORC1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: VKORC1 antibody can be used for detection of VKORC1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: VKORC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: VKORC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu VKORC1

Target: VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))

Andere Bezeichnung: VKORC1

Hintergrund: VKORC1 Antibody: Vitamin K epoxide reductase complex subunit 1 (VKORC1) is the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form which is essential for blood clotting. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is VKORC1 that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance.

Gen-ID: 79001

NCBI Accession: NP_076869

UniProt: Q9BQB6