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VEZT encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Zusätzlich bieten wir Ihnen Vezatin, Adherens Junctions Transmembrane Protein Kits (6) und und viele weitere Produktgruppen zu diesem Protein an.
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We found a genetic association between rs11031006 (FSHB (zeige FSHB Antikörper)) SNP and endometriosis. WNT4 (zeige WNT4 Antikörper) and VEZT genes constitute the most consistently associated genes with endometriosis. In the present study, an association of rs7521902 (WNT4 (zeige WNT4 Antikörper)) and rs10859871 (VEZT) was confirmed in women with endometriosis at the genotypic but not the allelic level.
This study identified the most effective small activating RNA via real-time PCR and Western blot. The selected small activating RNA inhibited the growth, invasion and migration of gastric cancer cells by specially reactivating VEZT.
VEZT expression levels can be considered as a biomarker for gastric cancer progression, lymphatic metastasis and as a novel independent prognostic factor.
vezatin and nearby SNP rs10859871 may have a role in endometriosis [meta-analysis]
VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.
miR (zeige MLXIP Antikörper)-43c directly targets adherens junctions' transmembrane protein (VEZT) and suppresses VEZT protein expression.
These results suggest a role of Vezatin in dendritic spine morphogenesis and functional synaptic maturation.
present study suggests that vezatin may regulate dendritic formation as a downstream effector of ARF6 (zeige ARF6 Antikörper).
vezatin associates with actin filaments at cell-cell junctions.
These in vitro observations reinforce the idea that homozygous vezatin-null mutants die at the time of implantation because of a defect in intercellular adhesion.
This gene encodes a transmembrane protein which has been localized to adherens junctions and shown to bind to myosin VIIA. Examination of expression of this gene in gastric cancer tissues have shown that expression is decreased which appears to be related to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants.
vezatin, adherens junctions transmembrane protein
, transmembrane protein vezatin