VEZT Antikörper (AA 480-530)

Produktnummer ABIN6992059

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VEZT in ELISA, WB, IHC (p) und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für VEZT Antikörper (AA 480-530) (ABIN6992059)

Target: VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEZT Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-VEZT Antikörper

Bindungsspezifität: AA 480-530

Spezifität: VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.

Aufreinigung: VEZT antibody is affinity chromatography purified via peptide column.

Immunogen: VEZT antibody was raised against a 17 amino acid peptide near the center of human VEZT. The immunogen is located within amino acids 480 - 530 of VEZT.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: VEZT antibody can be used for detection of VEZT by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: VEZT antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: VEZT antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu VEZT

Target: VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))

Andere Bezeichnung: VEZT

Hintergrund: Vezatin (VEZT) is a transmembrane protein which localizes to adherens junctions and binds to myosin VIIA and the cadherin-catenins complex (1). Expression of this gene in gastric cancer tissues is decreased due to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts (2). VEZT has also been shown to be required for morphogenesis of the preimplantation mouse embryo (3).

Molekulargewicht: Predicted: 63, 68, 78, 81, 83, 86 kDa

Observed: 60 kDa

Gen-ID: 55591

NCBI Accession: NP_060069

UniProt: Q9HBM0