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Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Zusätzlich bieten wir Ihnen VPS16 Antikörper (48) und und viele weitere Produktgruppen zu diesem Protein an.
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Vps16p is highly expressed in neurons of various brain areas and developmental stages tested; it colocalizes with microtubule associated protein 2, but not glial fibrillary acidic protein (zeige GFAP Proteine).
VPS16 is a new causative gene for adolescent-onset primary dystonia.
HOPS (zeige ALPL Proteine) subunit Vps16 recruits Vps33A (zeige VPS33A Proteine) to the human HOPS (zeige ALPL Proteine) complex; residues 642-736 are necessary and sufficient for this interaction.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Two transcript variants encoding different isoforms have been found for this gene.
vacuolar protein sorting protein 16
, vacuolar protein sorting-associated protein 16 homolog
, vacuolar protein sorting 16 homolog (S. cerevisiae)
, vacuolar protein sorting 16 homolog A