anti-V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Antikörper

VTCN1 encodes a protein belonging to the B7 costimulatory protein family. Zusätzlich bieten wir Ihnen VTCN1 Proteine (37) und VTCN1 Kits (28) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
VTCN1 242122 Q7TSP5
VTCN1 79679 Q7Z7D3
VTCN1 295322 Q501W4
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Top anti-VTCN1 Antikörper auf antikoerper-online.de

Showing 10 out of 208 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert ELISA, WB ABIN334524 (0.3µg/ml) staining of Human Spleen lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$350.00
Details
Human Ziege Unkonjugiert CyTOF, FACS, WB Detection of Mouse and Human B7-H4 by Western Blot. Western blot shows lysates of mouse placenta tissue, mouse uterus tissue, and SK-BR-3 human breast cancer cell line. PVDF membrane was probed with 2 ug/mL of Goat Anti-Mouse B7-H4 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.30
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of VTCN1 Antibody (Center) in T47D cell line lysates (35 µg/lane). VTCN1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Immunohistochemistry: B7-H4 Antibody [NBP2-30536] - Immunohistochemical staining of human kidney shows strong membranous and cytoplasmic positivity in cells in tubules. Immunohistochemistry-Paraffin: B7-H4 Antibody  - Staining of human breast shows moderate membranous positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human thyroid carcinoma labeled Anti-B7H4 Polyclonal Antibody, Unconjugated (ABIN671736) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled Anti-B7H4 Polyclonal Antibody, Unconjugated (ABIN671736) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details
Human Maus Unkonjugiert FACS   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$154.95
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB B7-H4 staining in human lung cancer. Paraffin-embedded human lung cancer tissue is stained with B7-H4 Antibody used at 1:200 dilution. 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$367.00
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus FITC FACS 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$577.50
Details

VTCN1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-VTCN1 Antikörper

  1. Human Polyclonal VTCN1 Primary Antibody für IHC, ELISA - ABIN1584048 : Basta, Galazka, Mach, Jozwicki, Walentowicz, Wicherek: The immunohistochemical analysis of RCAS1, HLA-G, and B7H4-positive macrophages in partial and complete hydatidiform mole in both applied therapeutic surgery and surgery followed by chemotherapy. in American journal of reproductive immunology (New York, N.Y. : 1989) 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Monoclonal VTCN1 Primary Antibody für FACS - ABIN2688846 : Sica, Choi, Zhu, Tamada, Wang, Tamura, Chapoval, Flies, Bajorath, Chen: B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. in Immunity 2003 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal VTCN1 Primary Antibody für IHC, IHC (p) - ABIN4282807 : Xu, Zhang, Zhang, Liu, Yin, Liu, Zhuo: Clinical relevance of expression of B7-H1 and B7-H4 in ovarian cancer. in Oncology letters 2016 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal VTCN1 Primary Antibody für CyTOF, FACS - ABIN4900129 : Radichev, Maneva-Radicheva, Amatya, Salehi, Parker, Ellefson, Burn, Savinov: Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 2 Pubmed References

  5. Mouse (Murine) Polyclonal VTCN1 Primary Antibody für FACS, WB - ABIN4900128 : Lee, Scandiuzzi, Ray, Wei, Hofmeyer, Abadi, Loke, Lin, Yuan, Serreze, Allison, Zang: B7x in the periphery abrogates pancreas-specific damage mediated by self-reactive CD8 T cells. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal VTCN1 Primary Antibody für FACS, IF (p) - ABIN671736 : Maskey, Li, Hu, Xu, Peng, Yu, Cao, Chen, Li, Yang: Impact of neoadjuvant chemotherapy on lymphocytes and co-inhibitory B7-H4 molecule in gastric cancer: low B7-H4 expression associates with favorable prognosis. in Tumour biology 2014 (PubMed)

  7. Human Polyclonal VTCN1 Primary Antibody für ELISA, WB - ABIN451629 : Krambeck, Thompson, Dong, Lohse, Park, Kuntz, Leibovich, Blute, Cheville, Kwon: B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  8. Human Monoclonal VTCN1 Primary Antibody für FACS - ABIN2477567 : van de Ven, van den Hout, Lindenberg, Sluijter, van Leeuwen, Lougheed, Meijer, van den Tol, Scheper, de Gruijl: Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation. in Blood 2011 (PubMed)

Weitere Antikörper gegen VTCN1 Interaktionspartner

Mouse (Murine) V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Interaktionspartner

  1. this study shows that B7-H4 knockout hosts mount greater tumor-associated anti-tumor T cell responses and display reduced tumors

  2. Results highlight an importance of VTCN1 stabilization on cell surfaces for the restoration of altered balance of immune control during T1D.

  3. Ablation of B7-H3 (zeige CD276 Antikörper) but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

  4. B7-H4 expression by nonhematopoietic cells in the tumor microenvironment promotes antitumor immunity.

  5. that B7x can modulate kidney damage in autoimmune diseases including lupus nephritis and anti-glomerular basement membrane disease

  6. B7-H4 can inhibit both antitumor T cells and protumor myeloid-derived suppressor cells (

  7. The endogenous expression of B7-H4 in donor beta cells from transgenic mice prolongs islet allograft survival, confirming the negative role of B7-H4 in regulating alloreactive T-cell responses.

  8. Local overexpression of B7x on pancreatic beta cells is sufficient to abolish CD8 (zeige CD8A Antikörper) T cell-induced diabetes.

  9. B7-H4 expression may influence the outcome of T-cell tumor cell interactions. Tumor-associated macrophage induced membrane-bound B7-H4 on lung cancer cell represents a novel mechanism by which lung cancer cells evade immune recognition and destruction.

  10. Overexpression of B7-H4 was shown in tumor infiltrated dendritic cells.

Human V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1) Interaktionspartner

  1. The decrease of B7-H4 expression in salivary glands of Sjogren's syndrome patients contributes to the defect of negatively regulating the inflammation caused by CD4 (zeige CD4 Antikörper)(+) T cells.

  2. Preclinical investigation into B7-H4-specific chimeric antigen receptor (CAR) T cells, antibody-mediated blockade of B7-H4, and anti-B7-H4 drug conjugates has shown antitumor efficacy in mouse models.

  3. This meta-analysis demonstrated that high B7-H4 expression is an unfavorable prognostic factor in NSCLC.

  4. This meta-analysis clarified that high B7-H4 expression in tissue was significantly associated with poor survival in patients with solid tumors.

  5. in pulmonary adenocarcinoma presenting with SPN (zeige SPN Antikörper), nuclear membrane localization of B7-H4 within the tumor cells is associated with increased malignancy

  6. Study reportes that B7-H3 (zeige CD276 Antikörper) and B7-H4 are highly expressed in human esophageal cancer tissues and significantly associated with tumor invasion.

  7. Results revealed B7-H4 to be associated with poor prognosis in patients with pancreatic cancer liver metastasis. B7-H4 may promote pancreatic cancer metastasis.

  8. PD-L1 (zeige CD274 Antikörper), IDO-1 (zeige IDO1 Antikörper), and B7-H4 are differentially expressed in human lung carcinomas and show limited co-expression. While PD-L1 (zeige CD274 Antikörper) and IDO-1 (zeige IDO1 Antikörper) are associated with increased tumor-infiltrating lymphoycte and IFN-gamma (zeige IFNG Antikörper) stimulation, B7-H4 is not.

  9. B7-H4 activation on Mphis/microglia in the microenvironment of gliomas is an important immunosuppressive event blocking effective T-cell immune responses.

  10. Knockdown of B7-H4 significantly up-regulated 57 miRNAs and down-regulated 14 miRNAs.

VTCN1 Antigen-Profil

Protein Überblick

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit VTCN1

  • V set domain containing T cell activation inhibitor 1 L homeolog (vtcn1.L) Antikörper
  • V-set domain containing T cell activation inhibitor 1 (VTCN1) Antikörper
  • V-set domain containing T-cell activation inhibitor 1 (VTCN1) Antikörper
  • V set domain containing T cell activation inhibitor 1 (vtcn1) Antikörper
  • V-set domain containing T cell activation inhibitor 1 (Vtcn1) Antikörper
  • B7-H4 Antikörper
  • B7h.5 Antikörper
  • B7H4 Antikörper
  • B7S1 Antikörper
  • B7X Antikörper
  • BC032925 Antikörper
  • PRO1291 Antikörper
  • RGD1311204 Antikörper
  • VCTN1 Antikörper

Bezeichner auf Proteinebene für VTCN1

V-set domain-containing T-cell activation inhibitor 1 , V-set domain containing T cell activation inhibitor 1 , V-set domain containing T-cell activation inhibitor 1 , immune costimulatory protein B7-H4 , t cell costimulatory molecule B7x , B7 family member, H4 , B7 superfamily member 1 , T cell costimulatory molecule B7x , T-cell costimulatory molecule B7x

GENE ID SPEZIES
379070 Xenopus laevis
418323 Gallus gallus
469433 Pan troglodytes
493551 Xenopus (Silurana) tropicalis
242122 Mus musculus
79679 Homo sapiens
295322 Rattus norvegicus
Ausgewählte Anbieter für anti-VTCN1 (VTCN1) Antikörper
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