Protein Überblick

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit UBA3

• ubiquitin like modifier activating enzyme 3 (UBA3) Antikörper
• ubiquitin-like modifier activating enzyme 3 (Uba3) Antikörper
• ubiquitin-like modifier activating enzyme 3 (uba3) Antikörper
• ubiquitin like modifier activating enzyme 3 (uba3) Antikörper
• ubiquitin like modifier activating enzyme 3 S homeolog (uba3.S) Antikörper

• A830034N06Rik Antikörper
• AI256736 Antikörper
• AI848246 Antikörper
• AW546539 Antikörper
• hUBA3 Antikörper
• Alle Synonyme
• ube1c Antikörper
• wu:fb75e04 Antikörper
• wu:fc37b11 Antikörper
• zgc:55528 Antikörper

Bezeichner auf Proteinebene für UBA3

NEDD8-activating enzyme E1 catalytic subunit , NEDD8-activating enzyme E1C , Nedd8-activating enzyme hUba3 , UBA3, ubiquitin-activating enzyme E1 homolog , ubiquitin-activating enzyme 3 , ubiquitin-activating enzyme E1C (UBA3 homolog, yeast) , ubiquitin-activating enzyme E1C (homologous to yeast UBA3) , ubiquitin-like modifier-activating enzyme 3 , ubiquitin activating enzyme 3 , ubiquitin-activating enzyme E1C , ubiquitin-like modifier activating enzyme 3 , NEDD8-activating enzyme E1 catalytic subunit-like