anti-Ubiquitin Specific Peptidase 2 (USP2) Antikörper

USP2 encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. Zusätzlich bieten wir Ihnen USP2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP2 9099 O75604
USP2 53376 O88623
USP2 115771 Q5U349
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Top anti-USP2 Antikörper auf antikoerper-online.de

Showing 10 out of 135 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-USP2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human brain WB Suggested Anti-USP2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-USP2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HCT15 cell lysate WB Suggested Anti-USP2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: HCT15 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-USP2 Antibody (C-term L523) (ABIN388879) in K562 cell line lysates (35 µg/lane).USP2(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB UBP46 Antibody (C-term) (ABIN658082) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the UBP46 antibody detected the UBP46 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of USP2 Antibody (N-term) (ABIN388877) in HL60 cell line lysates (35 µg/lane). USP2 (arrow) was detected using the purified polyclonal antibody. IHC for USP2a in a formalin-fixed, paraffin-embedded human prostate sample. Cytoplasmic positive immunostaining was detected in tumor glands (ii), whereas in normal prostatic epithelium, USP2a expression was restricted to the basal layer. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB The anti-USP2 Antibody (C-term)(ABIN388878) is used in Western blot to detect USP2 in USP2-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). Western blot analysis of anti-USP2 Antibody (C-term) (ABIN388878) in HL60 cell line lysates (35 µg/lane).USP2(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$335.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details

USP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus) , , ,


Am meisten referenzierte anti-USP2 Antikörper

  1. Human Polyclonal USP2 Primary Antibody für IHC (p), WB - ABIN388879 : Stevenson, Sparks, Allende-Vega, Xirodimas, Lane, Saville: The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2. in The EMBO journal 2007 (PubMed)
    Show all 8 Pubmed References

  2. Human Polyclonal USP2 Primary Antibody für IHC (p) - ABIN2477040 : Bryc, Zlomaniec: [Direct magnification technic as a method of further improving the diagnostic value of cerebral angiography]. in Neurologia i neurochirurgia polska 1976 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal USP2 Primary Antibody für IHC (p), WB - ABIN388877 : Priolo, Tang, Brahamandan, Benassi, Sicinska, Ogino, Farsetti, Porrello, Finn, Zimmermann, Febbo, Loda: The isopeptidase USP2a protects human prostate cancer from apoptosis. in Cancer research 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal USP2 Primary Antibody für - ABIN1882149 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal USP2 Primary Antibody für WB - ABIN388878 : Alonso, Magyar, Wang, Bisello, Friedman: Ubiquitination-deubiquitination balance dictates ligand-stimulated PTHR sorting. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen USP2 Interaktionspartner

Human Ubiquitin Specific Peptidase 2 (USP2) Interaktionspartner

  1. Authors show here USP2 is expressed in quiescent and activated T-cells and its expression is 50% lower in CTCL (zeige TSPYL2 Antikörper) cell lines (MyLa2000, SeAx and Hut-78) than in normal T-cells.

  2. Data show that ubiquitin variants (Ubvs) that bind to USP2 or USP21 (zeige USP21 Antikörper) contain a similar core functional epitope, or "hot spot," consisting mainly of positions that are conserved as the wild type sequence, but also some positions that prefer mutant sequences.

  3. The results show a connection between miR (zeige MLXIP Antikörper)-125b and USP2 gene the etiology of psoriasis. They proceeded to show that modulation of nuclear factor kappa B-mediated inflammation is the likely mechanism through which this miRNA gene pair function

  4. the deubiquitinase USP2a translocates into the nucleus and binds to pY701-STAT1 (zeige STAT1 Antikörper), and inhibits K48-linked ubiquitination and degradation of pY701-STAT1 (zeige STAT1 Antikörper)

  5. ML364 also caused a decrease in homologous recombination-mediated DNA repair. These effects by a small molecule inhibitor support a key role for USP2 as a regulator of cell cycle (zeige C13orf15 Antikörper), DNA repair, and tumor cell growth.

  6. Identify USP2 as a novel regulator of lipoprotein clearance owing to its ability to control ubiquitylation-dependent degradation of the LDLR (zeige LDLR Antikörper) by IDOL (zeige MYLIP Antikörper).

  7. Data suggest up-regulation of ASAH1 (acid ceramidase (zeige ASAH1 Antikörper)) activity by androgen in androgen-sensitive prostate cancer cells (but not other cancer cells) is mainly due to prolonged stability of ASAH1 (zeige ASAH1 Antikörper) by androgen-stimulated induction of USP2 expression.

  8. Modulation of USP-2 expression plays a crucial role in cell cycle regulation by leptin and adiponectin.

  9. The present study showed that USP2 expression is associated with TNBC cell line's invasiveness and poor survival of breast cancer patients and may serve as a prognostic biomarker and therapeutic target for TNBC

  10. findings demonstrated that USP2b deubiquitinates K63-linked polyubiquitin (zeige UBB Antikörper) chains from TBK1 (zeige TBK1 Antikörper) to terminate TBK1 (zeige TBK1 Antikörper) activation and negatively regulate IFN-beta (zeige IFNB1 Antikörper) signaling and antiviral immune response.

Mouse (Murine) Ubiquitin Specific Peptidase 2 (USP2) Interaktionspartner

  1. Usp2 is required for the PTH1 (zeige PTH Antikörper)-34-induced proliferation of osteoblasts

  2. Usp2 is a clock output effector related to bodily Ca2 (zeige CA2 Antikörper)+ homeostasis, a feature that is conserved across evolution.

  3. A novel function of USP2 in the molecular clock in which it regulates PER1 (zeige PER1 Antikörper) function.

  4. A role for USP2-45 as a central regulator of MR, able to remove the receptor monoubiquitylation and induced its destabilization.

  5. Data suggest that USP2 does not play a primary role in the control of sodium balance or blood pressure.

  6. a functional liver clock is required for the proper nutritional and circadian regulation of USP2-45 expression; at the molecular level, transcriptional coactivators PGC-1alpha and PGC-1beta (zeige PPARGC1B Antikörper) and repressor E4BP4 (zeige NFIL3 Antikörper) exert opposing effects on USP2-45 promoter activity

  7. USP2a potentially mediates circadian disruption by suppressing the CRY1 (zeige CRY1 Antikörper) degradation during inflammation.

  8. Rhythmic expression of USP2 in the SCN (zeige SRI Antikörper) and other tissues offers a new level of control of the clock machinery through de-ubiqutinylation and suggests a role for USP2 during circadian adaptation to environmental day length changes

  9. severe defect in the ability of Usp2 -/- spermatozoa to fertilize eggs

  10. TNFalpha (zeige TNF Antikörper)-induced USP2 down-regulation is an effective cytoprotective mechanism in hepatocytes.

USP2 Antigen-Profil

Protein Überblick

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit USP2

  • ubiquitin specific peptidase 2 (USP2) Antikörper
  • ubiquitin specific peptidase 2 (Usp2) Antikörper
  • B930035K21Rik Antikörper
  • UBP-t Antikörper
  • Ubp41 Antikörper
  • UBP46 Antikörper
  • ubp52 Antikörper
  • ubp66 Antikörper
  • USP9 Antikörper

Bezeichner auf Proteinebene für USP2

41 kDa ubiquitin-specific protease , deubiquitinating enzyme 2 , ubiquitin carboxyl-terminal hydrolase 2 , ubiquitin specific protease 12 , ubiquitin specific protease 9 , ubiquitin thioesterase 2 , ubiquitin-specific-processing protease 2 , ubiquitin specific protease 2 , ubiquitin thiolesterase 2 , ubiquitin-specific-processing protease testis , family of cysteine protease , ubiquitin specific protease 41 , ubiquitin specific protease 46 , ubiquitin specific protease 52 , ubiquitin specific protease 66

GENE ID SPEZIES
9099 Homo sapiens
53376 Mus musculus
115771 Rattus norvegicus
522980 Bos taurus
395766 Gallus gallus
Ausgewählte Anbieter für anti-USP2 (USP2) Antikörper
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